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Home β€Ί Medicine β€Ί Ninlib 150mg Capsule
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Ninlib 150mg Capsule

Prescription Required
Salt Composition NILOTINIB
Marketer HETERO HEALTHCARE LTD
Prepaid Only. Non-Returnable.
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Introduction to Ninlib 150mg Capsule

Ninlib 150mg Capsule is an antineoplastic medication containing the active ingredient Nilotinib. It belongs to the class of tyrosine kinase inhibitors. This medicine is used to treat Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), a type of blood cancer characterized by abnormal white blood cell production.

It is prescribed for adult and pediatric patients who are newly diagnosed with CML, those who experience side effects from previous treatments, or patients whose condition no longer responds to prior therapy, including Imatinib.

Before taking Ninlib:

Do not take this medicine if you are allergic to Nilotinib or any of its ingredients.

Inform your doctor if you have a history of heart conditions (such as heart attack, abnormal heart rhythms, chest pain), stroke, or poor blood flow in the legs (claudication).

Notify your doctor about liver or pancreas disorders, or if you have low potassium or magnesium levels.

Share a list of all medications you are taking, especially cholesterol-lowering drugs.

Inform your doctor if you have a history of hepatitis B infection, as this medicine can reactivate the virus, which may be serious.

Avoid grapefruit and grapefruit juice.

If you have lactose intolerance, inform your doctor, as the capsule contains lactose.

During treatment:
Your doctor may perform regular blood tests to monitor:

Liver and pancreas function

Blood cell counts (WBC, RBC, platelets)

Heart health, including QT interval monitoring

Electrolytes (potassium, magnesium, etc.)

Blood sugar and lipid levels

Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Use effective contraception during treatment with Ninlib.

Uses of Ninlib 150mg Capsule

Blood cancer (Philadelphia chromosome-positive chronic myeloid leukemia) in adults and pediatrics.

Therapeutic Effects of Ninlib 150mg Capsule

BCR-ABL tyrosine kinase is responsible for the uncontrolled division of cells in the CML. Ninlib 150mg disrupts the signaling route of the protein kinase enzyme which targets the BCR-ABL protein and inhibits the growth and spread of cancer cells.

Interaction of Ninlib 150mg Capsule with other drugs

Inform your healthcare professional about all the medicines you take, including prescription, over-the-counter, nutritional and vitamin supplements, and herbal products. Certain medications such as antiarrhythmics, chloroquine, Titonavir, Carbamazepine, or any other drugs, interacting with Ninlib 150mg may reduce effectiveness by causing undesirable side effects.

More Information about Ninlib 150mg Capsule

Keep this medicine out of the sight and reach of children and pets Do not store above 30Β°C Keep it in its original packaging in order to protect it from light and moisture. During treatment, you may also have a high level of liver enzymes, urea, or insulin. Contact your doctor immediately if you experience any unusual symptoms.

How to consume Ninlib 150mg Capsule

Take Ninlib 150mg as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking Ninlib 150mg unless your doctor advises you to stop.

Side Effects of Ninlib 150mg Capsule

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
Sudden weight gain
Swelling in hands, feet, ankles, or face
Chest pain
Blood pressure (high and low)
Discoloration of tongue, lips, or skin (blue)
Abnormal heart (irregular heartbeat)
Hair loss
Vision problem
Stomach pain, vomiting of blood, blood in stools.
Yellowing of the skin, eyes, and dark urine.
High blood sugar levels.
Sensitivity to light
Common
Nausea, vomiting, diarrhoea.
Headache, muscle pain, stomach pain.
Hair loss.
Tiredness.
Constipation.
Slowing of growth in children.
Pneumonia.
Loss of appetite.
Sleeplessness, depression, and anxiety.
Stomach discomforts like bloating and flatulence after meals.
musculoskeletal pain

Safety Advice for Ninlib 150mg Capsule

Breast Feeding
Unsafe
Taking Ninlib 150mg while breastfeeding may be unsafe because it may affect the child. Therefore, talk with your doctor to get more information.
Alcohol-Consult your doctor
Alcohol
Consult Your Doctor
It is unknown whether consuming alcohol while taking a Ninlib 150mg capsule is safe. Please speak with your physician.
Liver-Consult your doctor
Liver
Consult Your Doctor
Inform your physician if you have liver problems because Ninlib 150mg should be used cautiously with this condition. Before starting treatment, your physician conduct the liver function test.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
It is unknown if patients with lung conditions can consume Ninlib 150mg. So, before beginning the treatment, consult your doctor if you have any lung conditions. Consult your doctor if you experience symptoms like difficulty in breathing, wheezing or any other lung related condition while taking Ninlib 150mg.
Driving-Consult your doctor
Driving
Consult Your Doctor
While taking Ninlib 150mg, it is unsafe to drive or use machines because it may cause nausea, changes in vision, vomiting, etc. Talk to your doctor for more information.
Pregnancy-unsafe
Pregnancy
Unsafe
Ninlib 150mg is unsafe to use during pregnancy unless it is necessary. Report to your doctor if you are pregnant or think you may be pregnant, or planning for the pregnancy before starting the treatment; your doctor will tell you whether you can take this medicine during your pregnancy.

Word of Advice for Ninlib 150mg Capsule

Based on your condition your doctor may prescribe a lower dose. Ninlib 150mg can be used by people aged 65 years and over with the same dose as other adults. Tell your doctor if you experience any irregular heartbeats or any signs of a heart condition because this can lead to serious complications like sudden death. Inform your physician if you have kidney problems. Your physician will decide whether you may receive this medication after monitoring your kidney functions. Some children and adolescents taking this medicine may have slower than normal growth. So, your doctor will regularly monitor your growth. Report to your doctor if you have had a history of heart failure or hepatitis infection. Discuss effective contraceptive options with your healthcare provider.

FAQs about Ninlib 150mg Capsule

Q1. Q1. Can Ninlib 150mg cause liver damage?

Ninlib 150mg may cause liver function abnormalities, which may indicate liver damage. It is important to have regular blood tests to monitor your liver function while taking Ninlib 150mg. If you experience symptoms of liver damage, such as jaundice or abdominal pain, you should contact your doctor immediately.

Q2. Q2. How does Ninlib 150mg differ from other medications used to treat chronic myeloid leukemia, such as Imatinib?

Imatinib, in its selectivity and potency. Ninlib 150mg is more selective for the BCR-ABL protein that drives the growth of cancer cells, and it is more potent in inhibiting the activity of this protein. This medicine has also been shown to be effective in patients who have developed resistance to Imatinib.

Q3. Q3. What are the potential long-term effects of Ninlib 150mg on the body?

The potential long-term effects of Ninlib 150mg on the body include cardiovascular events, such as hypertension, arrhythmias, and heart failure, as well as liver dysfunction, pancreatic enzyme elevation, and fluid retention. These side effects are generally rare, but they can occur in some patients.

Q4. Q4. How to monitor the effects of Ninlib 150mg over the course of treatment?

It is monitored through regular blood tests, electrocardiograms, and imaging studies. Blood tests can assess liver and kidney function, blood counts, and electrolyte levels. ECG can detect any changes in heart rhythm or function. Imaging studies, such as echocardiograms and chest X-rays, can evaluate the heart and lungs for any signs of damage or fluid accumulation.

Q5. Q5. Who should not take Ninlib 150mg?

Ninlib 150mg should not be taken by pregnant or breastfeeding women, or by people with certain medical conditions such as severe liver or kidney disease, a history of pancreatitis, or a prolonged QT interval.

Fact Box of Ninlib 150mg Capsule

Molecule Name NILOTINIB
Marketer HETERO HEALTHCARE LTD

References for Ninlib 150mg Capsule

1.Robert J. Thomson; Majid Moshirfar; Yasmyne Ronquillo; Tyrosine Kinase Inhibitors, [Revised on 21st Jan 2021]; [Accessed on 22st April 2023]
2.Novartis Pharmaceuticals UK Ltd, Electronic Medicines Compendium (EMC), [Revised on May 2022], [Accessed on 21st April 2023],
3.Novartis, US Food & Drug Administration, [Revised on Sep 2021], [Accessed on 21st April 2023],
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