Yervoi 50mg Injection

Prescription Required Cold Chain i

Salt Composition IPILIMUMAB

Marketer BRISTOL MYERS SQUIBB

Prepaid Only. Non-Returnable.

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Introduction to Yervoi 50mg Injection

Yervoi 50mg Injection is a pharmaceutical preparation containing IPILIMUMAB as its active ingredient, classified under the Anti Cancer general category and the Oncology speciality domain. Ipilimumab is a monoclonal antibody that blocks CTLA-4, an immune checkpoint receptor on T-cells, removing an inhibitory brake on the immune system and enhancing T-cell mediated anti-tumour activity. Manufactured by BRISTOL MYERS SQUIBB. As with any prescription medicine, dosage and treatment duration must be individualised by the treating specialist based on the patient's diagnosis, disease stage, organ function, and concurrent medications.

Uses of Yervoi 50mg Injection

Uses of Yervoi 50mg Injection
Used for the treatment of advanced (unresectable or metastatic) melanoma, and in combination regimens for other cancers such as renal cell carcinoma, as directed by the treating oncologist.

Therapeutic Effects of Yervoi 50mg Injection

Yervoi 50mg Injection containing IPILIMUMAB works as described: Ipilimumab is a monoclonal antibody that blocks CTLA-4, an immune checkpoint receptor on T-cells, removing an inhibitory brake on the immune system and enhancing T-cell mediated anti-tumour activity. Therapeutically, it is classified under the Anti Cancer category and Oncology speciality domain. Regular monitoring by the treating specialist is recommended to assess treatment response and manage side effects.

Interaction of Yervoi 50mg Injection with other drugs

• Always inform your doctor about every medicine, supplement, or herbal product you are currently taking before starting Yervoi 50mg Injection, since combined use with other drugs metabolised through similar pathways, or with other nephrotoxic/hepatotoxic/myelosuppressive agents, may increase the risk of side effects.

More Information about Yervoi 50mg Injection

Yervoi 50mg Injection is a prescription-only medicine and should be used strictly under the supervision of a licensed specialist. Storage: Store refrigerated at 2°C to 8°C. Do not freeze. Protect from light. Keep in the original carton until use. Disposal: Do not flush unused product or dispose of it in household waste; return unused or expired product to a licensed pharmacy. Manufactured by BRISTOL MYERS SQUIBB and complies with applicable drug regulatory standards. Pharmacovigilance: Report any unexpected or serious adverse effects to your doctor and to CDSCO in India through the online ADR reporting system.

How to consume Yervoi 50mg Injection

Administration: Administered as an intravenous infusion under close specialist supervision; this is a cold-chain product handled under a strict cold storage protocol. Missed Dose/Cycle: Contact your treatment centre or doctor promptly to reschedule; never double a dose to make up for a missed one. Overdose: In case of a suspected overdose or administration error, contact your doctor or nearest emergency facility immediately.

Side Effects of Yervoi 50mg Injection

Common: fatigue, diarrhoea, skin rash, and itching.

Serious/rare: immune-related adverse events including severe colitis, hepatitis, endocrinopathies (thyroiditis, hypophysitis), and pneumonitis.

Safety Advice for Yervoi 50mg Injection

Prescription Compliance: Take/use Yervoi 50mg Injection exactly as prescribed; do not self-adjust dose, frequency, or duration.

Drug Interactions: Inform your doctor about all other medicines, supplements, or herbal products you are taking before starting Yervoi 50mg Injection.

Medical History: Share your complete medical history, including heart, liver, and kidney conditions, before starting Yervoi 50mg Injection.

Pregnancy and Breastfeeding: Use only if specifically advised by your doctor, as many of these medicines are not safe during pregnancy or breastfeeding.

Safe Storage: Store refrigerated at 2°C to 8°C. Do not freeze. Protect from light. Keep in the original carton until use. Keep out of reach of children and pets. Do not use beyond the expiry date.

Word of Advice for Yervoi 50mg Injection

• Adherence is Key: Follow the prescribed schedule for Yervoi 50mg Injection and attend all scheduled treatment visits. • Report Changes: Contact your care team promptly if you notice new or worsening symptoms, especially those flagged as serious above. • Regular Monitoring: Complete all recommended blood tests and scans to track treatment response and organ function. • Do Not Share: Never share Yervoi 50mg Injection with another patient, even with a similar diagnosis, as dosing is individualised.

FAQs about Yervoi 50mg Injection

Q1. What is Yervoi 50mg Injection used for?

Used for the treatment of advanced (unresectable or metastatic) melanoma, and in combination regimens for other cancers such as renal cell carcinoma, as directed by the treating oncologist.

Q2. What are the common side effects?

Common: fatigue, diarrhoea, skin rash, and itching.

Q3. Is a prescription required?

Yes, prescription required.

Fact Box of Yervoi 50mg Injection

Molecule Name	IPILIMUMAB
Marketer	BRISTOL MYERS SQUIBB

References for Yervoi 50mg Injection

WHO Essential Medicines; Indian National Formulary; DrugBank; Mayo Clinic Drug Reference; BNF 2024

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