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Home β€Ί Medicine β€Ί Tishtha 100mg Injection

Tishtha 100mg Injection

Prescription Required Cold Chain i
Salt Composition NIVOLUMAB
Marketer ZYDUS
Prepaid Only. Non-Returnable.
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Introduction to Tishtha 100mg Injection

Tishtha 100mg Injection contains the active ingredient nivolumab, an immunotherapy medicine used in the treatment of various cancers, including cancers of the skin, lungs, kidneys, lymph nodes, bladder, esophagus, and urinary tract. It may be prescribed when cancer has returned or progressed after previous treatments such as surgery, chemotherapy, or radiation therapy.

Nivolumab works by strengthening the body’s immune response against cancer. It targets and blocks specific proteins that normally reduce the immune system’s ability to detect and destroy cancer cells. By inhibiting these proteins, the medicine enhances the immune system’s capacity to recognize and attack tumor cells, which may help slow or reduce tumor growth.

Benefits of Treatment
One advantage of Tishtha and other immunotherapy medicines is their potential to produce long-lasting responses in some patients, even after treatment has ended. This differs from traditional chemotherapy or radiation therapy, which often provide temporary effects and may be associated with more pronounced side effects.

Contraindications and Precautions
Tishtha 100mg Injection should not be used in patients who have experienced a severe allergic reaction to nivolumab or any of its ingredients.

It is also generally not recommended for individuals with certain autoimmune disorders, such as lupus or rheumatoid arthritis, as it may further stimulate the immune system and worsen these conditions.

Caution is advised in patients with a history of organ transplantation, since activating the immune system could increase the risk of organ rejection.

Patients should always inform their healthcare provider about their full medical history before starting treatment.

Uses of Tishtha 100mg Injection

Advanced skin cancer (melanoma)

Skin cancer that recurs after surgery

Advanced non-small cell lung cancer

Advanced kidney cancer

Hodgkin’s lymphoma (lymph node disease)

Advanced cancer of the head and neck

Advanced urinary tract and bladder cancer

Advanced oesophageal cancer

Therapeutic Effects of Tishtha 100mg Injection

This medication acts on specific receptors to provide therapeutic relief.

Interaction of Tishtha 100mg Injection with other drugs

Systemic corticosteroids (Oral/Injection Route) Moderate Use with caution unless advised by a doctor. Concomitant use may reduce the effectiveness of nivolumab by suppressing the immune system. Other immunosuppressants (Oral/Injection Route) Moderate Use only if clearly prescribed. Concomitant use may decrease the immune response and reduce the anticancer effect of nivolumab. Other immune checkpoint inhibitors (Injection Route) Moderate Use only under specialist supervision. Concomitant use may increase immune-related side effects such as inflammation of organs. Live vaccines (Injection Route) Moderate Avoid during treatment. Concomitant use may increase the risk of infection because immune responses can be altered during ther

More Information about Tishtha 100mg Injection

Regular monitoring of symptoms and follow-ups with your healthcare provider are recommended.

How to consume Tishtha 100mg Injection

Tishtha 100mg Injection is a medication a healthcare professional administers, typically in a hospital or clinic setting. The medication is given as an intravenous (IV) infusion by healthcare professional. The infusion typically takes several hours. You will be closely monitored during and after the infusion to ensure the medication works effectively and to watch for any side effects. The dosage and frequency of administration will depend on the condition being treated and your circumstances. Your healthcare provider will determine the appropriate dosage and schedule for you.

Side Effects of Tishtha 100mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
Pneumonitis (inflammation of lung tissue)
Colitis (inflammation of the colon)
Hepatitis (inflammation of the liver)
Hypothyroidism
Hyperthyroidism
Adrenal insufficiency (a condition in which the adrenal glands do not produce enough hormones).
Severe allergic reactions
Infusion-related reactions
Confusion
Seizures
Neuropathy
Eye disorders (such as uveitis or iritis)
Common:
Fatigue
Nausea
Skin rash
Itching
Loss of appetite
Diarrhea
Constipation
Joint pain
Headache

Safety Advice for Tishtha 100mg Injection

Breast Feeding
Consult Your Doctor
It is unknown whether Tishtha 100mg Injection is excreted in human breast milk, so a breastfeeding woman should discuss the potential risks and benefits of the medication with their healthcare provider before starting treatment.
Alcohol-Consult Your Doctor
Alcohol
Consult Your Doctor
There are no known interactions between Tishtha 100mg Injection and alcohol. However, it is generally recommended to avoid consuming alcohol while being treated for a medical condition, as alcohol can potentially interfere with the effectiveness of the medication and increase the risk of side effects.
Liver-Unsafe
Liver
Unsafe
Tishtha 100mg Injection should be used cautiously in individuals with liver disease, as the medication is primarily metabolized in the liver and could potentially worsen liver function. Your healthcare provider will monitor you closely if you have liver disease and adjust your dosage if necessary.
Lungs-Unsafe
Lungs
Unsafe
Tishtha 100mg Injection should be used cautiously in individuals with lung disease, as the medication can potentially worsen lung function. Your healthcare provider will monitor you closely if you have lung disease and adjust your dosage if necessary. If you have lung disease or a history of respiratory problems, discussing the potential risks and benefits of treatment with your healthcare provider is important. Your healthcare provider may recommend additional monitoring or testing to ensure the medication is not causing any adverse effects on your lungs.
Driving-Unsafe
Driving
Unsafe
Patients receiving Tishtha 100mg Injection should avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.
Pregnancy-Unsafe
Pregnancy
Unsafe
Tishtha 100mg Injection is unsafe for a developing foetus and is not recommended during pregnancy as it can cause harm to the developing foetus.

Word of Advice for Tishtha 100mg Injection

Discuss the potential risks and benefits of Tishtha 100mg Injection with your healthcare provider before or during treatment. Follow all safety precautions and guidelines given by your healthcare provider to reduce possible risks. Report any new or worsening symptoms to your healthcare provider immediately, as some side effects may be serious. Women of reproductive age should use effective contraception during treatment and for at least 5 months after the last dose to prevent harm to a developing fetus. Take care of your overall health during treatment. Eat a balanced diet, get enough rest, and seek support from family, friends, or support groups.

FAQs about Tishtha 100mg Injection

Q1. Q1. Can Tishtha 100mg Injection Cause Skin Reactions?

Some patients receiving Tishtha 100mg Injection may experience skin reactions such as rash, itching, or blistering. These side effects should be reported to a healthcare provider as they may require treatment.

Q2. Q2. Can Tishtha 100mg Injection Cause Infertility?

There is limited data on the long-term effects of Tishtha 100mg Injection on fertility. However, the medication may impact fertility in some patients, particularly those receiving high doses or long-term treatment. Patients concerned about their fertility should discuss their options with a healthcare provider.

Q3. Q3. Can Tishtha 100mg Injection Cause Diabetes?

Tishtha 100mg Injection may cause changes in blood sugar levels, leading to diabetes in some patients. Patients should be monitored closely for changes in their blood sugar levels during treatment.

Q4. Q4. Can Tishtha 100mg Injection be Used in Children?

Tishtha 100mg Injection is not currently approved for use in children. However, some clinical trials are underway to evaluate the safety and effectiveness of the medication in pediatric patients.

Q5. Q5. How Does Tishtha 100mg Injection Compare to other Immunotherapy medications?

Tishtha 100mg Injection is one of several immunotherapy medications that are used to treat cancer. The specific medication used may depend on several factors, including the type and stage of the cancer being treated and the patient's response to treatment. Patients should discuss their options with a healthcare provider to determine the best treatment plan for their situation.

Q6. Q6. How Is Tishtha 100mg Injection Different from Chemotherapy?

Tishtha 100mg Injection is an immunotherapy that enhances the body's natural immune response to cancer cells. Chemotherapy, on the other hand, works by killing cancer cells directly. While both treatments may be used in combination for some types of cancer, they work in different ways and may have different side effects.

Q7. Q7. How Often Are Patients Monitored During Tishtha 100mg Injection Treatment?

Patients receiving Tishtha 100mg Injection treatment will typically be monitored closely for any signs of adverse reactions or changes in their cancer status. This may include regular blood tests, imaging studies, and physical exams.

Fact Box of Tishtha 100mg Injection

Molecule Name NIVOLUMAB
Marketer ZYDUS

References for Tishtha 100mg Injection

1.Harrison's Principles of Internal Medicine. 20th edition, 2018, 929-932
2.Bristol-Myers Squibb, U.S. Food and Drug Administration, Nivolumab, [ Last updated, 4 April 2023]. [ Accessed on 4 April]
3.Goodman & Gilman's The Pharmacological Basis of Therapeutics. 12th edition, 2011,1655-1660
4.Takeda UK Ltd, Electronic Medicines Compendium (emc), Opdivo 10 mg/mL concentrate for solution for infusion, [Last updated: 30 October 2020], [Accessed on 4 April 2023],
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Tishtha 100mg Injection
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4 ML Injection in Vial
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