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PEGYLATED LIPOSOMAL IRINOTECAN
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Onivyde 43mg Injection

Prescription Required Cold Chain i
Salt Composition PEGYLATED LIPOSOMAL IRINOTECAN
Marketer SERVIER INDIA PRIVATE LIMITED
Prepaid Only. Non-Returnable.
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This medicine is prepaid
only and cannot be
returned once delivered.
16% OFF
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Introduction to Onivyde 43mg Injection

Onivyde 43mg Injection is a pharmaceutical preparation containing PEGYLATED LIPOSOMAL IRINOTECAN as its active ingredient, classified under the Anti Cancer general category and the Oncology speciality domain. Pegylated liposomal irinotecan is a topoisomerase I inhibitor encapsulated in a liposomal formulation, which increases circulation time and preferentially delivers the drug to tumour tissue, causing DNA damage and cancer cell death. Manufactured by SERVIER INDIA PRIVATE LIMITED. As with any prescription medicine, dosage and treatment duration must be individualised by the treating specialist based on the patient's diagnosis, disease stage, organ function, and concurrent medications.

Uses of Onivyde 43mg Injection

Uses of Onivyde 43mg Injection
Used, usually in combination with fluorouracil and leucovorin, for the treatment of metastatic pancreatic cancer after prior gemcitabine-based therapy.

Therapeutic Effects of Onivyde 43mg Injection

Onivyde 43mg Injection containing PEGYLATED LIPOSOMAL IRINOTECAN works as described: Pegylated liposomal irinotecan is a topoisomerase I inhibitor encapsulated in a liposomal formulation, which increases circulation time and preferentially delivers the drug to tumour tissue, causing DNA damage and cancer cell death. Therapeutically, it is classified under the Anti Cancer category and Oncology speciality domain. Regular monitoring by the treating specialist is recommended to assess treatment response and manage side effects.

Interaction of Onivyde 43mg Injection with other drugs

โ€ข Always inform your doctor about every medicine, supplement, or herbal product you are currently taking before starting Onivyde 43mg Injection. Strong CYP3A4/UGT1A1 inhibitors or inducers can significantly alter drug levels and toxicity; caution with other myelosuppressive drugs.

More Information about Onivyde 43mg Injection

Onivyde 43mg Injection is available under medical guidance and should be used strictly as advised by a licensed specialist. Storage: Store between 2ยฐC and 8ยฐC. Do not freeze. Protect from light. Disposal: Do not flush unused product or dispose of it in household waste; return unused or expired product to a licensed pharmacy. Manufactured by SERVIER INDIA PRIVATE LIMITED and complies with applicable regulatory standards.

How to consume Onivyde 43mg Injection

Administration: Administered as an intravenous infusion by a healthcare professional as per the prescribed cycle. Missed Dose/Cycle: Contact your treatment centre promptly to reschedule; never double a dose to make up for a missed one. Overdose: In case of a suspected overdose or administration error, contact your doctor or nearest emergency facility immediately.

Side Effects of Onivyde 43mg Injection

Common: diarrhoea, nausea, vomiting, and low blood counts.
Serious/rare: severe neutropenia with infection, severe diarrhoea with dehydration, and severe infusion reactions.

Safety Advice for Onivyde 43mg Injection

Prescription Compliance: Take/use Onivyde 43mg Injection exactly as prescribed; do not self-adjust dose, frequency, or duration.
Drug Interactions: Strong CYP3A4/UGT1A1 inhibitors or inducers can significantly alter drug levels and toxicity; caution with other myelosuppressive drugs.
Medical History: Share your complete medical history, including heart, liver, and kidney conditions, before starting Onivyde 43mg Injection.
Pregnancy and Breastfeeding: Use only if specifically advised by your doctor, as many of these medicines are not safe during pregnancy or breastfeeding.
Safe Storage: Store between 2ยฐC and 8ยฐC. Do not freeze. Protect from light. Keep out of reach of children and pets. Do not use beyond the expiry date.

Word of Advice for Onivyde 43mg Injection

โ€ข Adherence is Key: Follow the prescribed schedule for Onivyde 43mg Injection and attend all scheduled treatment visits. โ€ข Report Changes: Contact your care team promptly if you notice new or worsening symptoms, especially those flagged as serious above. โ€ข Regular Monitoring: Complete all recommended blood tests and scans to track treatment response and organ function. โ€ข Do Not Share: Never share Onivyde 43mg Injection with another patient, even with a similar diagnosis, as dosing is individualised.

FAQs about Onivyde 43mg Injection

Q1. What is Onivyde 43mg Injection used for?

Used, usually in combination with fluorouracil and leucovorin, for the treatment of metastatic pancreatic cancer after prior gemcitabine-based therapy.

Q2. What are the common side effects?

Common: diarrhoea, nausea, vomiting, and low blood counts.

Q3. Is a prescription required?

Yes, prescription required.

Fact Box of Onivyde 43mg Injection

Molecule NamePEGYLATED LIPOSOMAL IRINOTECAN
MarketerSERVIER INDIA PRIVATE LIMITED

References for Onivyde 43mg Injection

WHO Essential Medicines; Indian National Formulary; DrugBank; Mayo Clinic Drug Reference; BNF 2024
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Onivyde 43mg Injection
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1 Vial of 10ml Injection in Vial
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