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Home β€Ί Medicine β€Ί Koselugo 25mg Capsule
Substitutes
Koselugo 10mg Capsule
ASTRAZENECA PHARMA
β‚Ή335,200.00
60% cheaper

Koselugo 25mg Capsule

Prescription Required
Salt Composition SELUMETINIB
Marketer ASTRAZENECA PHARMA
Prepaid Only. Non-Returnable.
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This medicine is prepaid
only and cannot be
returned once delivered.
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Introduction to Koselugo 25mg Capsule

Koselugo 25mg Capsule contains the active ingredient Selumetinib. It is a prescription medication used to treat certain types of cancers, including melanoma (skin cancer) and other solid tumors, such as non-small cell lung cancer and ovarian cancer, particularly in cases where a specific genetic mutation makes the cancer cells sensitive to MEK inhibitors.

Koselugo may be prescribed for patients with advanced melanoma carrying specific genetic mutations, often BRAF-mutant melanoma. It has also shown effectiveness in treating plexiform neurofibromas, which are tumors linked to NF1, a genetic disorder that causes tumors to develop along nerves.

Precautions and Warnings:

Do not take Koselugo if you have had a severe allergic reaction to Selumetinib or any of its ingredients.

This medicine may harm an unborn baby and is not recommended during pregnancy.

Patients with pre-existing heart conditions or a history of heart problems may require close monitoring, and in some cases, may not be suitable for this treatment.

Older adults, particularly those over 65 years, may be at a higher risk for certain side effects.

Close medical monitoring is recommended during treatment to detect any adverse reactions.

The safety and effectiveness in children below specific ages has not been fully established.

Uses of Koselugo 25mg Capsule

Uses of Koselugo 25mg Capsule

Melanoma treatment
Neurofibromatosis type 1 (NF1)
Solid tumor treatment

Therapeutic Effects of Koselugo 25mg Capsule

Koselugo 25mg Capsule is a medication that targets a specific cellular pathway called the MEK pathway, which is crucial for regulating cell growth. In cancers like melanoma and certain tumors, it blocks this pathway, disrupting signals that promote uncontrolled cell growth. By inhibiting this pathway, it slows down or halts the progression of cancer cells, reducing tumor growth and spread.

Interaction of Koselugo 25mg Capsule with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the Koselugo 25mg Capsule, reducing effectiveness by causing undesirable side effects.

More Information about Koselugo 25mg Capsule

Stored at controlled room temperature, between 20Β°C to 25Β°C Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets.

How to consume Koselugo 25mg Capsule

Koselugo 25mg Capsule is primarily administered orally, typically as capsules. The healthcare provider will determine the dosage and duration of treatment based on the specific infection and individual factors.

Side Effects of Koselugo 25mg Capsule

Koselugo 25mg Capsule causes some side effects like all medications, although not everyone will experience them.
Serious:
Heart problems
Eye problems
Interstitial lung disease (ILD)
Liver problems
Skin toxicities
Common:
Nausea and vomiting
Diarrhea
Fatigue
Skin rash
Swelling or fluid retention

Safety Advice for Koselugo 25mg Capsule

Breast Feeding
Unsafe
It is not safe to breastfeed while taking Koselugo 25mg Capsule, as it may pass into breast milk and harm the infant.
Alcohol-Consult your doctor
Alcohol
Consult Your Doctor
There are no specific interactions between alcohol and Koselugo 25mg Capsule, but alcohol consumption might exacerbate certain side effects, such as dizziness or liver-related problems. It is advisable to consult a healthcare professional regarding alcohol consumption while on this medication.
Liver-Consult your doctor
Liver
Consult Your Doctor
If you have a liver condition or are concerned about the safety of Koselugo 25mg Capsule, it is recommended to consult your healthcare provider for personalized advice.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
Consult your health care provider before taking Koselugo 25mg Capsule if you have lung disease.
Driving-unsafe
Driving
Unsafe
Taking Koselugo 25mg Capsule while driving is unsafe as it might cause dizziness or visual disturbances as side effects, which could affect the ability to drive or operate machinery.
Pregnancy-unsafe
Pregnancy
Unsafe
It is not safe to take Koselugo 25mg Capsule during pregnancy as it may cause harm to the unborn baby.

Word of Advice for Koselugo 25mg Capsule

Regular monitoring of heart function, including ECGs and cardiac assessments, may be necessary due to potential heart-related side effects while using Koselugo 25mg Capsule. Periodic eye exams are recommended as this medication might cause vision changes or retinal vein occlusion. Patients require monitoring for signs of interstitial lung disease (ILD) or breathing difficulties. Monitoring liver function through blood tests is essential due to the potential for elevated liver enzymes or liver damage. Live vaccines should generally be avoided during treatment due to potential complications. Regular monitoring might be necessary for individuals with existing endocrine conditions. Discuss with a healthcare professional regarding other medications, including over-the-counter drugs, herbal supplements, or vitamins, to avoid potential interactions with this medication.

FAQs about Koselugo 25mg Capsule

Q1. Q1. What are the common side effects of Koselugo 25mg Capsule?

Common side effects of Koselugo 25mg Capsule may include nausea, vomiting, diarrhea, fatigue, skin rash, and swelling.

Q2. Q2. Are there any dietary restrictions while taking Koselugo 25mg Capsule?

No specific dietary restrictions are known while taking Koselugo 25mg Capsule, but following a balanced diet is advisable unless otherwise instructed by a healthcare professional.

Q3. Q3. What should I do if I miss a dose of Koselugo 25mg Capsule?

If you miss a dose of Koselugo 25mg Capsule, take it as soon as you remember unless it's close to the next scheduled dose. Do not double the dose to catch up. Contact your healthcare provider for guidance.

Q4. Q4. How long does it take for Koselugo 25mg Capsule to work?

The response to Koselugo 25mg Capsule can vary among individuals. Some may experience a reduction in tumor size or symptoms within weeks to months, while others may take longer to see noticeable effects.

Q5. Q5. Can Koselugo 25mg Capsule cure cancer?

Koselugo 25mg Capsule is a treatment that aims to control the growth and spread of cancer cells. It may shrink tumors and improve symptoms, but its ability to completely cure cancer varies based on individual circumstances and the type and stage of cancer.

Q6. Q6. How often must I undergo medical tests while taking Koselugo 25mg Capsule?

The frequency of medical tests for Koselugo 25mg Capsule, such as blood tests or imaging studies, will depend on individual factors and your healthcare provider's recommendations. Monitoring is often necessary to manage potential side effects and track treatment progress.

Fact Box of Koselugo 25mg Capsule

Molecule Name SELUMETINIB
Marketer ASTRAZENECA PHARMA

References for Koselugo 25mg Capsule

1.MARC R THEORET, Food and Drug Administration (FDA),[Revised on April 2020] [ Accessed on 15th Nov 2023]
2.AstraZeneca UK Limited, Electronic medicines compendium (EMC), [ Revised on 15 Mar 2023] [ Accessed on 15th Nov 2023],
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Koselugo 25mg Capsule
β‚Ή838,000.00 MRP β‚Ή1,021,992.19
Inclusive of all taxes 18% OFF
(You Save β‚Ή183,992.19)
60 Cap Capsule in Bottle

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