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Home β€Ί Medicine β€Ί Kadcyla 100mg Injection
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Kadcyla 100mg Injection

Prescription Required
Salt Composition ADO-TRASTUZUMAB EMTANSINE
Marketer Marketer ROCHE PRODUCTS
Prepaid Only. Non-Returnable.
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This medicine is prepaid
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Introduction to Kadcyla 100mg Injection

Kadcyla 100mg Injection contains the active ingredient Ado-Trastuzumab Emtansine. It is a prescription medication used to treat HER2-positive breast cancer, particularly in cases where the cancer has spread to other parts of the body or has not responded to previous treatments.

Kadcyla is a combination therapy, consisting of trastuzumab, an antibody that specifically targets HER2 receptors, and emtansine, a chemotherapy agent that kills cancer cells. It is indicated for both early-stage and advanced-stage breast cancer, including patients who experience cancer recurrence within six months of completing chemotherapy. Kadcyla works against tumors that produce higher than normal levels of the HER2 protein.

Patients with residual breast cancer after chemotherapy and HER2-targeted therapy generally have a poorer prognosis compared to those with no residual disease.

Side Effects and Precautions:

Report immediately to your physician if you experience allergic reactions, unusual bleeding, or other severe symptoms.

Kadcyla generally does not affect kidney function.

Rarely, patients may experience infusion reactions during administration.

Common mild side effects include nausea, vomiting, diarrhea, and hair loss.

Uses of Kadcyla 100mg Injection

Kadcyla Injection is indicated for its use in the following conditions:

Advanced and metastatic breast cancer
Metastatic gastric cancer

Therapeutic Effects of Kadcyla 100mg Injection

Ado-Trastuzumab emtansine works by combining the targeting ability of trastuzumab, which binds to HER2-positive cancer cells, with the cell-killing effects of emtansine, a chemotherapy drug. Once this medication binds to the HER2-positive cancer cells, it releases emtansine, which then enters the cancer cells and destroys them. This process helps to slow down or stop the growth of cancer, reducing the size of tumors and potentially extending the patient's life.

Interaction of Kadcyla 100mg Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Kadcyla 100mg and cause undesirable side effects.

More Information about Kadcyla 100mg Injection

Kadcyla 100mg Injection should be stored in refrigerator at 2Β°C to 8Β°C (36Β°F to 46Β°F). Protected from light. Keep it in its original packaging until it is ready to be used. Keep reaching out of the reach of children and pets. It should be disposed of properly.

How to consume Kadcyla 100mg Injection

adcyla 100mg Injection is administered by a healthcare professional in a hospital or clinic setting. The dose and frequency depend on several factors, such as the individual's age, weight, overall health, and the type and stage of the cancer being treated.

Side Effects of Kadcyla 100mg Injection

Kadcyla side effects can range from anywhere between mild and serious. Here's what to know:
Serious:
Infusion reactions, including fever, chills, rash, or difficulty breathing
Lung problems, including shortness of breath, cough, or fever
Heart problems, including heart failure or abnormal heart rhythms
Severe bleeding or bruising
Nerve damage, including numbness, tingling, or weakness
Severe allergic reactions
Common:
Fatigue
Nausea
Constipation
Muscle or joint pain
Headache
Fever
Low platelet count
High liver enzyme levels
Low red blood cell count
Loss of appetite
Rash or itching

Safety Advice for Kadcyla 100mg Injection

Breast Feeding
Unsafe
Avoid breastfeeding your baby while on the treatment with Kadcyla 100mg Injection at least seven months after the final dose.
Alcohol-unsafe
Alcohol
Unsafe
It is recommended to avoid consuming alcohol while taking Kadcyla 100mg Injection, as alcohol can increase the risk of certain side effects associated with the medication, such as stomach ulcers or gastrointestinal bleeding.
Liver-unsafe
Liver
Unsafe
Kadcyla 100mg Injection can affect liver function, and in rare cases, it can cause liver damage, including hepatotoxicity and liver failure. Therefore, it's important to inform your healthcare professional if you have any history of liver problems, such as hepatitis or cirrhosis, before starting treatment.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
Kadcyla 100mg Injection safety and efficacy have not been extensively studied. So patients with pre-existing lung conditions should consult a doctor before taking it.
Driving-unsafe
Driving
Unsafe
Kadcyla 100mg Injection can cause unusual tiredness and dizziness. Hence, it is advised to avoid driving or handling machinery during the treatment.
Pregnancy-unsafe
Pregnancy
Unsafe
Discuss with your physician before taking this Kadcyla 100mg Injection if you are pregnant or think you might be pregnant. Do not take this medicine during the pregnancy unless advised by the doctor to take as it may cause harm to the unborn baby.

Word of Advice for Kadcyla 100mg Injection

If you are receiving Kadcyla 100mg Injection, it's important to be proactive in managing your treatment and monitoring your symptoms. Keep communication with your healthcare provider and report any concerns or side effects as soon as possible. Avoid getting pregnant and breastfeeding during treatment. Use effective birth control during the treatment and at least 7 weeks after the last dose. Immediately contact your healthcare provider in case of any worsening of symptoms or infusion reactions. Take steps to care for yourself physically and emotionally during treatment, and seek support from loved ones and professionals as needed. Maintain a healthy and balanced diet during treatment to support your overall health and well-being. Being informed and engaged in your treatment can help ensure the best possible outcomes and manage potential risks or complications.

FAQs about Kadcyla 100mg Injection

Q1. Q1. Can Kadcyla 100mg Injection cause nerve damage?

Kadcyla 100mg Injection can cause peripheral neuropathy, a type of nerve damage that can cause tingling, numbness, or weakness in the hands and feet. If you experience these symptoms during treatment, discuss them with your healthcare provider.

Q2. Q2. Does Kadcyla 100mg Injection cause infertility?

Kadcyla 100mg Injection can cause temporary infertility in some patients, particularly women. If fertility preservation is a concern for you, discuss this with your healthcare provider before starting treatment.

Q3. Q3. How is Kadcyla 100mg Injection different from traditional chemotherapy?

Kadcyla 100mg Injection is a type of chemotherapy, but it is designed to target HER2-positive cancer cells specifically, which may result in fewer side effects than traditional chemotherapy. Additionally, it is given as a single medication, rather than as a combination of drugs.

Q4. Q4. Can Kadcyla 100mg Injection be used in combination with other cancer treatments?

Kadcyla 100mg Injection may be used in combination with other cancer treatments, such as chemotherapy or targeted therapies. Your healthcare provider can help determine the best treatment plan for you based on your individual needs and medical history.

Q5. Q5. Can I take Kadcyla 100mg Injection if I have tuberculosis?

The use of Kadcyla 100mg Injection in patients with active tuberculosis (TB) is not recommended due to the risk of worsening the TB infection. This medication can suppress the immune system, making it harder for the body to fight off infections such as TB. Before starting treatment, your healthcare provider will perform a thorough evaluation of your medical history, including screening for TB.

Q6. Q6. Can Kadcyla 100mg Injection cause heart problems?

Kadcyla 100mg Injection can cause heart problems, particularly in patients with preexisting heart conditions or risk factors. Your healthcare provider will monitor your heart function closely during treatment.

Q7. Q7. Does Kadcyla injection cause hair loss?

Kadcycla 100mg injection might lead to hairfall and bald patches due to continued usage. Consult your doctor if you are experiencing something specific or need a detailed breakdown on what to expect.

Q8. Q8. What is the cost of Kadcyla and its MRP in India?

The Kadcyla cost in India is influenced by its market price, with the Kadcyla price having an MRP of Rs. 171,963. This price may vary depending on the pharmacy and any applicable discounts or insurance coverage.

Fact Box of Kadcyla 100mg Injection

Molecule Name ADO-TRASTUZUMAB EMTANSINE
Marketer Marketer ROCHE PRODUCTS

References for Kadcyla 100mg Injection

1.Roche Products Limited, Electronic Medicines Compendium (EMC), [Revised on Jul 2021] [Accessed on 9th April 2023],
2.Gunter von Minckwitz et al., Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer, N Engl J Med 2019; 380:617-628 [Accessed on 19th April 2023],
3.Barok et al., Trastuzumab emtansine: mechanisms of action and drug resistance, Breast Cancer Research 2014, 16:209, [Accessed on 19th April 2023],
4.Genentech, Inc. U.S Food and Drug Administration (FDA) [Last Revised 3rd May 2019], [Accessed on 19 April 2023],
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Kadcyla 100mg Injection
β‚Ή128,927.00 MRP β‚Ή161,215.31
Inclusive of all taxes 20% OFF
(You Save β‚Ή32,288.31)
0 ML Injection in Vial

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