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Home β€Ί Medicine β€Ί Crizalk 250mg Capsule

Crizalk 250mg Capsule

Prescription Required
Salt Composition CRIZOTINIB
Marketer PFIZER
Prepaid Only. Non-Returnable.
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This medicine is prepaid
only and cannot be
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Introduction to Crizalk 250mg Capsule

Crizalk 250mg Capsules contain the active ingredient Crizotinib and belong to the class of tyrosine kinase inhibitors, a type of anticancer (antineoplastic) medicine. This medication is used to treat patients with Anaplastic Lymphoma Kinase (ALK)-positive non-small cell lung cancer (NSCLC) that is locally advanced or metastatic, meaning the cancer has spread beyond the lungs to other parts of the body.

Precautions Before Use

Allergies: Do not take this medicine if you are allergic to Crizotinib or any of its components.

Medical History: Inform your doctor if you have a history of kidney, stomach, heart, or liver problems.

Other Conditions: Notify your physician if you have low white blood cell counts, abnormal ECG readings, vision issues, or are taking other medications.

Pregnancy, Fertility, and Contraception

Discuss with your doctor if you are planning to become pregnant or think you might be pregnant.

Effective contraception is mandatory during treatment, as oral contraceptives may not be reliable. Continue using birth control for at least 90 days after completing therapy.

Consult your physician regarding fertility preservation, as this medicine may impact reproductive health.

Usage Guidelines

Crizalk 250mg is not recommended for adolescents or children under 18 years.

Protect your skin from sunlight using sunscreen or protective clothing, as Crizotinib can increase sensitivity to UV exposure.

Pricing and Availability

The price of Crizalk 250mg may vary depending on the seller and location.

Uses of Crizalk 250mg Capsule

Crizalk 250mg uses are:

Anaplastic lymphoma kinase (ALK) positive non-small cell lung cancer (NSCLC)

Therapeutic Effects of Crizalk 250mg Capsule

Therapeutic Effects of Crizalk 250mg Capsules Crizalk 250mg is a targeted anticancer medication that works by inhibiting the Anaplastic Lymphoma Kinase (ALK) protein, which plays a key role in the growth and survival of certain lung cancer cells. Key Therapeutic Effects: Blocks Cancer Cell Growth: Crizotinib interferes with ALK signaling pathways, preventing the uncontrolled multiplication of cancer cells. Slows Tumor Progression: By targeting ALK-positive cancer cells, Crizalk helps control tumor growth and reduces the risk of further spread (metastasis). Reduces Tumor Size: Treatment with Crizalk can lead to shrinkage of existing tumors, improving breathing, chest discomfort, and other lung-related symptoms. Effective Against Metastatic Disease: It works even when the cancer has spread beyond the lungs, offering a targeted approach for advanced stages of NSCLC. Supports Symptom Management: By controlling tumor activity, Crizalk may help relieve coughing, chest pain, shortness of breath, and improve overall quality of life. Overall Effect: Crizalk 250mg provides a targeted therapy approach, focusing on ALK-positive lung cancer cells while minimizing damage to normal cells, making it an effective treatment option for advanced or metastatic ALK-positive NSCLC.

Interaction of Crizalk 250mg Capsule with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications such as Erythromycin, Diltiazem, Verapamil, and other medications may interact with Crizalk 250mg and reduce its effectiveness by causing undesirable side effects.

More Information about Crizalk 250mg Capsule

Follow Your Prescription Carefully: Take Crizalk 250mg exactly as prescribed by your doctor. Do not alter the dose or stop taking it without consulting your healthcare provider. Allergy Awareness: Do not use this medicine if you are allergic to Crizotinib or any other ingredients in the capsule. Report any signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, immediately. Medical History Matters: Inform your doctor if you have a history of kidney, liver, heart, or stomach problems, or if you experience vision issues, low white blood cell counts, or abnormal ECG results. Pregnancy and Contraception: Discuss fertility and pregnancy plans with your doctor before starting treatment. Use effective birth control during therapy and for at least 90 days after finishing Crizalk, as oral contraceptives may not be reliable. Women who are pregnant or planning pregnancy should not take this medication. Children and Adolescents: Crizalk 250mg is not recommended for patients under 18 years. Sun Protection: This medication may increase sensitivity to sunlight. Use sunscreen, hats, or protective clothing when outdoors to avoid sunburn. Drug Interactions: Inform your doctor about all medications, including over-the-counter drugs, vitamins, or herbal supplements, to avoid potential interactions. Regular Monitoring: Your doctor may schedule blood tests, ECGs, and vision exams to monitor your response to treatment and detect side effects early. Report Symptoms Promptly: Contact your doctor immediately if you notice

How to consume Crizalk 250mg Capsule

Crizotinib in Crizalk 250mg by Pfizer is a tyrosine kinase inhibitor that works by blocking the activity of the anaplastic lymphoma kinase (ALK) protein. It specifically targets the abnormal protein and blocks its activity, slowing down or stopping the growth and spread of cancer cells.

Side Effects of Crizalk 250mg Capsule

Crizalk 250mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Crizalk 250mg side effects are:
Serious
Pain on the right of the stomach
Partial or full loss of vision
Lowered WBC
Low heart rate.
Swelling of the lungs.
Breathlessness
Cough with or without mucus
Common
Sensitivity to sunlight.
Diarrhea
Fever
Constipation
Nausea
Increased liver enzymes
Decreased appetite Tiredness (fatigue)
Dizziness
Neuropathy (weakness, tingling, or numbness in the nerve)
Dysgeusia ( taste disorder)
Hypophosphataemia (low levels of phosphate in the blood)

Safety Advice for Crizalk 250mg Capsule

Breast Feeding
Unsafe
It is unsafe to breastfeed while taking Crizalk 250mg capsule because it can cause toxicity to the baby. Consult your physician for more information.
Alcohol-Consult your doctor
Alcohol
Consult Your Doctor
It is not known whether it is safe to consume alcohol with Crizalk 250mg capsule. Please consult your doctor.
Liver-Consult your doctor
Liver
Consult Your Doctor
Inform your physician about any underlying liver disorders before taking Crizalk 250mg capsule, as this medication should be used with caution in liver disease patients. Consult your physician before taking this medicine.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
Inform your doctor immediately if you experience any symptoms like lung inflammation, difficulties in breathing, cough with or without mucous, or even fever while taking Crizalk 250mg capsule.
Driving-unsafe
Driving
Unsafe
It is unsafe to drive while taking Crizalk 250mg capsule because this medicine might cause dizziness and tiredness, so avoid driving and operating machinery during this treatment.
Pregnancy-unsafe
Pregnancy
Unsafe
Crizalk 250mg capsule medicine is unsafe to use during pregnancy. Hence, check with your physician before taking this medicine if you are pregnant or think you might be pregnant.

Word of Advice for Crizalk 250mg Capsule

Follow Your Prescription Carefully: Take Crizalk 250mg exactly as prescribed by your doctor. Do not alter the dose or stop taking it without consulting your healthcare provider. Allergy Awareness: Do not use this medicine if you are allergic to Crizotinib or any other ingredients in the capsule. Report any signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, immediately. Medical History Matters: Inform your doctor if you have a history of kidney, liver, heart, or stomach problems, or if you experience vision issues, low white blood cell counts, or abnormal ECG results. Pregnancy and Contraception: Discuss fertility and pregnancy plans with your doctor before starting treatment. Use effective birth control during therapy and for at least 90 days after finishing Crizalk, as oral contraceptives may not be reliable. Women who are pregnant or planning pregnancy should not take this medication. Children and Adolescents: Crizalk 250mg is not recommended for patients under 18 years. Sun Protection: This medication may increase sensitivity to sunlight. Use sunscreen, hats, or protective clothing when outdoors to avoid sunburn. Drug Interactions: Inform your doctor about all medications, including over-the-counter drugs, vitamins, or herbal supplements, to avoid potential interactions. Regular Monitoring: Your doctor may schedule blood tests, ECGs, and vision exams to monitor your response to treatment and detect side effects early. Report Symptoms Promptly: Contact your doctor immediately if you notice

FAQs about Crizalk 250mg Capsule

Q1. Q1. Does Crizalk 250mg capsule cure cancer?

Crizalk 250mg capsule is not a cure for cancer, but it can help to slow down or stop the growth and spread of cancer cells, improving the overall survival and quality of life of patients with certain types of cancer.

Q2. Q2. What should I do if I miss a dose of Crizalk 250mg capsule?

If you miss a dose of Crizalk 250mg capsule, you should take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Q3. Q3. What should I tell my doctor before taking Crizalk 250mg capsule?

Before taking Crizalk 250mg capsule, you should tell your doctor if you have liver or kidney problems, a history of heart disease, or are pregnant or planning to become pregnant.

Q4. Q4. Why there are low levels of phosphate in the blood while taking Crizalk 250mg capsule?

The exact mechanism by which the Crizalk 250mg capsule causes hypophosphatemia (low level of phosphate) is not fully understood, but it is thought to be related to the inhibition of certain enzymes involved in phosphate transport and metabolism in the body.

Q5. Q5. Can Crizalk 250mg capsule be used in combination with other cancer medications?

Crizalk 250mg capsule may be used in combination with the chemotherapy drugs Pemetrexed and Cisplatin in the first-line treatment of ALK-positive non-small cell lung cancer (NSCLC). It depends on the specific cancer diagnosis and treatment plan.

Fact Box of Crizalk 250mg Capsule

Molecule Name CRIZOTINIB
Marketer PFIZER

References for Crizalk 250mg Capsule

1.David Eric Gerber, ECOG-ACRIN Cancer Research Group, ClinicalTrials.gov IDNCT02201992 [Accessed on 30th Mar 2021],
2.Pfizer, Electronic Medicines Compendium (EMC), [Revised on Jun 2022], [Accessed on 19th April 2023]
3.Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.
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Crizalk 250mg Capsule
β‚Ή84,350.00 MRP β‚Ή106,602.30
Inclusive of all taxes 21% OFF
(You Save β‚Ή22,252.30)
60 Cap Capsule in Bottle
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