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Home β€Ί Medicine β€Ί Crizalk 200mg Capsule
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Crizalk 250mg Capsule
PFIZER
β‚Ή84,350.00
8% costlier

Crizalk 200mg Capsule

Prescription Required
Salt Composition CRIZOTINIB
Marketer PFIZER
Prepaid Only. Non-Returnable.
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This medicine is prepaid
only and cannot be
returned once delivered.
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Introduction to Crizalk 200mg Capsule

Crizalk 200mg contains the active ingredient Crizotinib and belongs to the class of tyrosine kinase inhibitors, a type of antineoplastic (anticancer) medicine. This drug is prescribed for the treatment of Anaplastic Lymphoma Kinase (ALK)-positive non-small cell lung cancer (NSCLC) that is locally advanced or metastatic, meaning it has spread beyond the lungs to other parts of the body.

Precautions Before Use

Allergies: Do not take this medicine if you are allergic to Crizotinib or any of its components.

Medical History: Inform your doctor if you have a history of kidney, stomach, heart, or liver problems.

Other Health Concerns: Notify your physician if you have low white blood cell counts, abnormal ECG readings, vision issues, or if you are taking other medications.

Pregnancy, Fertility, and Contraception

Discuss with your doctor if you are planning pregnancy or think you might be pregnant.

Effective contraception is mandatory during treatment, as oral contraceptives may not be reliable. Continue using birth control for at least 90 days after completing therapy.

Consult your doctor regarding fertility preservation options, as Crizotinib may affect reproductive health.

Usage Guidelines

This medication is not recommended for adolescents or children under 18 years.

Protect your skin from sunlight using sunscreen or protective clothing, as Crizotinib can increase sensitivity to UV exposure.

Availability and Alternatives

The price of Crizalk 200mg may vary depending on location and pharmacy.

Alternative medications for ALK-positive NSCLC include Xalkori, Alectinib, Ceritinib, Lorlatinib, and Brigatinib, which may be prescribed based on your doctor’s recommendation

Uses of Crizalk 200mg Capsule

Crizalk 200mg tablet uses are:

Anaplastic lymphoma kinase (ALK) positive non-small cell lung cancer (NSCLC)

Therapeutic Effects of Crizalk 200mg Capsule

Therapeutic Effects of Crizalk 200mg Capsules Crizalk 200mg is an anticancer medication that works by targeting Anaplastic Lymphoma Kinase (ALK), a protein that promotes the growth of cancer cells in certain types of non-small cell lung cancer (NSCLC). Key Therapeutic Effects: Inhibits Cancer Cell Growth: Crizotinib blocks the activity of the ALK enzyme, preventing cancer cells from multiplying uncontrollably. Slows Tumor Progression: By interfering with signals that drive tumor growth, Crizalk helps slow down the spread of cancer to other parts of the body. Reduces Tumor Size: In many patients, treatment can shrink existing tumors, improving symptoms and quality of life. Targets Metastatic Disease: Effective against ALK-positive NSCLC even when the cancer has spread beyond the lungs. Improves Symptom Management: Helps alleviate lung cancer-related symptoms such as shortness of breath, chest pain, and persistent cough by controlling tumor growth. Overall Effect: Crizalk 200mg provides a targeted therapy approach, focusing on cancer cells with the ALK mutation while sparing most normal cells, which can lead to better outcomes compared to traditional chemotherapy in ALK-positive NSCLC

Interaction of Crizalk 200mg Capsule with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications such as Erythromycin, Diltiazem, Verapamil, and other medications may interact with Crizalk 200mg and reduce its effectiveness by causing undesirable side effects.

More Information about Crizalk 200mg Capsule

Regular monitoring of symptoms and follow-ups with your healthcare provider are recommended.

How to consume Crizalk 200mg Capsule

Take the Crizalk 200mg capsules at about the same time each day. The recommended dose is one capsule of 250 mg taken orally twice daily. Swallow the capsules whole and do not crush, chew, dissolve, or open the capsules. Your physician will choose the Crizalk dosage and administration frequency based on the medical condition because it differs for each person.

Side Effects of Crizalk 200mg Capsule

Crizalk 200mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
Pain on the right of the stomach
Partial or full loss of vision
Lowered WBC
Low heart rate.
Swelling of the lungs.
Breathlessness
Cough with or without mucus
Common
Sensitivity to sunlight.
Diarrhea
Fever
Constipation
Nausea
Increased liver enzymes
Decreased appetite Tiredness (fatigue)
Dizziness
Neuropathy (weakness, tingling, or numbness in the nerve)
Dysgeusia ( taste disorder)
Hypophosphataemia (low levels of phosphate in the blood)

Safety Advice for Crizalk 200mg Capsule

Breast Feeding
Unsafe
It is unsafe to breastfeed while taking Crizalk 200mg capsule because it can cause toxicity to the baby. Consult your physician for more information.
Alcohol-Consult your doctor
Alcohol
Consult Your Doctor
It is not known whether it is safe to consume alcohol with Crizalk 200mg capsule. Please consult your doctor.
Liver-Consult your doctor
Liver
Consult Your Doctor
Inform your physician about any underlying liver disorders before taking Crizalk 200mg capsule, as this medication should be used with caution in liver disease patients. Consult your physician before taking this medicine.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
Inform your doctor immediately if you experience any symptoms like lung inflammation, difficulties in breathing, cough with or without mucous, or even fever while taking Crizalk 200mg capsule.
Driving-unsafe
Driving
Unsafe
It is unsafe to drive while taking Crizalk 200mg capsule because this medicine might cause dizziness and tiredness, so avoid driving and operating machinery during this treatment.
Pregnancy-unsafe
Pregnancy
Unsafe
Crizalk 200mg capsule is unsafe to use during pregnancy. Hence, check with your physician before taking this medicine if you are pregnant or think you might be pregnant.

Word of Advice for Crizalk 200mg Capsule

Take the Crizalk 200mg capsules at about the same time each day. The recommended dose is one capsule of 250 mg taken orally twice daily. Swallow the capsules whole and do not crush, chew, dissolve, or open the capsules. Your physician will choose the Crizalk dosage and administration frequency based on the medical condition because it differs for each person.

FAQs about Crizalk 200mg Capsule

Q1. Q1. Does Crizalk 200mg capsule cure cancer?

Crizalk 200mg capsule is not a cure for cancer, but it can help to slow down or stop the growth and spread of cancer cells, improving the overall survival and quality of life of patients with certain types of cancer

Q2. Q2. What should I do if I miss a dose of Crizalk 200mg capsule?

If you miss a dose of Crizalk 200mg capsule, you should take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Q3. Q3. What should I tell my doctor before taking Crizalk 200mg capsule?

Before taking Crizalk 200mg capsule, you should tell your doctor if you have liver or kidney problems, a history of heart disease, or are pregnant or planning to become pregnant.

Q4. Q4. Why there are low levels of phosphate in the blood while taking Crizalk 200mg capsule?

The exact mechanism by which Crizalk 200mg capsule causes hypophosphatemia (low level of phosphate) is not fully understood, but it is thought to be related to the inhibition of certain enzymes involved in phosphate transport and metabolism in the body.

Q5. Q5. Can Crizalk 200mg capsule be used in combination with other cancer medications?

Crizalk 200mg capsule may be used in combination with the chemotherapy drugs Pemetrexed and Cisplatin in the first-line treatment of ALK-positive non-small cell lung cancer (NSCLC). It depends on the specific cancer diagnosis and treatment plan.

Fact Box of Crizalk 200mg Capsule

Molecule Name CRIZOTINIB
Marketer PFIZER

References for Crizalk 200mg Capsule

1.David Eric Gerber, ECOG-ACRIN Cancer Research Group, ClinicalTrials.gov IDNCT02201992 [Accessed on 30th Mar 2021],
2.Pfizer, Electronic Medicines Compendium (EMC), [Revised on Jun 2022], [Accessed on 19th April 2023],
3.Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.
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Crizalk 200mg Capsule
β‚Ή78,354.00 MRP β‚Ή100,490.57
Inclusive of all taxes 22% OFF
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60 Cap Capsule in Bottle

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