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Home β€Ί Medicine β€Ί Cancrinase 3750IU Injection
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Cancrinase 3750IU Injection

Prescription Required Cold Chain i
Salt Composition PEGASPARGASE
Marketer MANKIND PHARMACEUTICALS LIMITED
Prepaid Only. Non-Returnable.
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Introduction to Cancrinase 3750IU Injection

Cancrinase 3750 IU Injection is a chemotherapy medication containing Pegaspargase as its active ingredient. It is used to treat Acute Lymphoblastic Leukemia (ALL), a type of blood cancer where immature white blood cells multiply uncontrollably, interfering with the production of healthy blood cells. When combined with other chemotherapy drugs, Cancrinase can help improve the chances of remission and long-term survival in patients with ALL. It is especially effective in children, who tend to have higher remission rates and better overall survival when this drug is included in their treatment plan.

Cancrinase 3750 IU Injection is usually administered alongside other chemotherapy agents, particularly for patients who have not responded to previous treatments or who experience a relapse after initial therapy. Some patients may develop glucose intolerance while on this medication. Contact your doctor promptly if you experience severe headaches, abdominal pain, increased thirst, or serious allergic reactions. Individuals with a history of kidney or pancreatic disorders should consult their healthcare provider before using this medicine.

Uses of Cancrinase 3750IU Injection

Acute Lymphoblastic Leukemia
Non-Hodgkin's Lymphoma

Therapeutic Effects of Cancrinase 3750IU Injection

Cancrinase 3750IU Injection is an enzyme that breaks down the amino acid asparagine in the body. Cancer cells require asparagine to grow and divide and cannot produce their asparagine. By breaking down asparagine in the body, this medication can effectively "starve" cancer cells of this essential nutrient, slowing their growth and promoting cancer cell death. However, normal cells in the body can produce their asparagine and are not as affected by the enzyme as cancer cells. Therefore, this medicine selectively targets cancer cells while sparing healthy cells in the body to some extent.

Interaction of Cancrinase 3750IU Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Cancrinase 3750IU Injection and reduce effectiveness by causing undesirable side effects.

More Information about Cancrinase 3750IU Injection

Store in a refrigerator at 2-8Β°C. Do not freeze. Protected from light. Keep it in its original packaging until it is ready to be used. Keep out of the reach of children and pets. Should be disposed of properly.

How to consume Cancrinase 3750IU Injection

Cancrinase 3750IU Injection is typically administered by a healthcare provider as an intravenous (IV) injection in a clinical setting. The dosage and frequency of infusions will vary depending on the patient's medical condition, age, weight, and other factors. You should not take a double dose to make up the second dose.

Side Effects of Cancrinase 3750IU Injection

Like all medications, Cancrinase 3750IU Injection can cause side effects, although not everyone who takes it will experience them.
Serious:
Anaphylaxis (severe allergic reaction)
Thrombosis (blood clots)
Hemorrhage (bleeding)
Tumor Lysis Syndrome (a potentially life-threatening condition due to the breakdown of cancer cells)
Acute pancreatitis (inflammation of the pancreas)
Hepatotoxicity (liver damage or failure)
Neurotoxicity (damage to the nervous system)
Hypersensitivity reactions (allergic reactions, including anaphylaxis)
Renal failure (kidney damage or failure)
Common:
Nausea
Vomiting
Diarrhea
Fatigue
Loss of appetite
Headache
Fever or chills
Muscle or joint pain
Rash or itching
Swelling or redness at the injection site

Safety Advice for Cancrinase 3750IU Injection

Breast Feeding
Consult Your Doctor
It is unclear whether Cancrinase 3750IU Injection is excreted in human milk. So you should consult a doctor before taking this medication if you are a breastfeeding mother.
Alcohol-unsafe
Alcohol
Unsafe
It is recommended to avoid consuming alcohol while taking Cancrinase 3750IU Injection, as alcohol can increase the risk of certain side effects associated with the medication, such as stomach ulcers or gastrointestinal bleeding.
Liver-Consult your doctor
Liver
Consult Your Doctor
Cancrinase 3750IU Injection is primarily metabolized in the liver, so inform your healthcare provider if you have any liver problems or diseases. This medication may also increase liver enzymes, which can be a sign of liver damage or inflammation. Patients taking this medication require regular blood tests to monitor liver function.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
There is no evidence to suggest that Cancrinase 3750IU Injection harms the lungs. However, as with any medication, there is a risk of side effects that could affect the respiratory system. So patients should consult their doctor if they have any pre-existing lung disease before taking this medication.
Driving-unsafe
Driving
Unsafe
Patients receiving Cancrinase 3750IU Injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.
Pregnancy-Consult your doctor
Pregnancy
Consult Your Doctor
There are no established adverse effects of Cancrinase 3750IU Injection in pregnant women. Consult your doctor if you are pregnant or planning to get pregnant before taking this medicine.

Word of Advice for Cancrinase 3750IU Injection

If you are receiving treatment with Cancrinase 3750IU Injection, report any side effects or concerns promptly. If you are pregnant or planning to become pregnant or breastfeeding, it is important to discuss the risks and benefits with your healthcare provider. If patients see any sign of jaundice (yellow skin and eyes, abdominal pain, vomiting) after taking this medication, they should contact a doctor immediately because it can cause pancreas inflammation. Patients require close monitoring for any signs of abnormal bleeding or clotting. Making lifestyle changes, such as quitting smoking, maintaining a healthy weight, and eating a healthy diet, can also help support your overall health and reduce the risk of cancer-related complications. Additionally, seeking support from family members, friends, or support groups can provide patients with emotional support and help them cope with the challenges of cancer treatment.

FAQs about Cancrinase 3750IU Injection

Q1. Q1. Can I take Cancrinase 3750IU Injection if I have diabetes?

Patients with diabetes may still be able to use Cancrinase 3750IU Injection, but caution is needed as the medication can cause glucose intolerance and hyperglycemia. Patients with a history of diabetes should be closely monitored for signs of high blood sugar, such as increased thirst, urination, and fatigue, during treatment.

Q2. Q2. Can I use Cancrinase 3750IU Injection if I have kidney disease?

Patients with kidney disease may still be able to use Cancrinase 3750IU Injection, but caution is needed as the medication can cause kidney toxicity. Dosing and monitoring may need to be adjusted based on the severity of kidney disease.

Q3. Q3. How will Cancrinase 3750IU Injection affect my blood?

Cancrinase 3750IU Injection can cause blood clotting disorders, leading to serious or life-threatening bleeding or clotting. Patients should be closely monitored for signs of abnormal bleeding or clotting.

Q4. Q4. Can Cancrinase 3750IU Injection be given to patients with a history of pancreatitis?

It depends on the severity and cause of the pancreatitis. Patients with a history of pancreatitis may be at increased risk of experiencing pancreatitis while using Cancrinase 3750IU Injection. However, if the benefits of using this medication outweigh the risks, it may sometimes be used with careful monitoring.

Q5. Q5. How long does the effect of Cancrinase 3750IU Injection last?

The effect of Cancrinase 3750IU Injection may last several weeks, depending on the patient's medical condition and response to treatment.

Fact Box of Cancrinase 3750IU Injection

Molecule Name PEGASPARGASE
Marketer MANKIND PHARMACEUTICALS LIMITED

References for Cancrinase 3750IU Injection

1.KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 868
2.Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1720
3.Les Laboratories Servier, Electronic medicines compendium (EMC), [ Revised on Nov 2021] [ Accessed on 25th April 2023],
4.Sigma-Tau Pharmaceuticals, US Food, and Drug Administration, [ Revised on March 2011] [ Accessed on 25th April 2023],
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Cancrinase 3750IU Injection
β‚Ή18,199.00 MRP β‚Ή22,790.61
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5 ML Injection in Vial

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