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Home β€Ί Medicine β€Ί Brukinsa 80mg Capsule
Substitutes

Brukinsa 80mg Capsule

Prescription Required
Salt Composition ZANUBRUTINIB
Marketer GLENMARK PHARMACEUTICALS LTD
Prepaid Only. Non-Returnable.
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This medicine is prepaid
only and cannot be
returned once delivered.
20% OFF
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Introduction to Brukinsa 80mg Capsule

Brukinsa 80mg Capsule is a prescription medication used to treat certain types of blood cancers. Its active ingredient is Zanubrutinib, which belongs to a class of drugs called BTK (Bruton's tyrosine kinase) inhibitors. These medications work by blocking a protein that supports cancer cell growth and survival, helping to slow or stop the spread of cancer in the body.

Usage:
Brukinsa is generally prescribed for patients who have already received other treatments for blood cancer. It is taken orally in capsule form. While it can be effective, it may not be suitable for everyone. People with severe liver problems, certain heart conditions, or women who are pregnant or breastfeeding should only use this medication if their doctor determines it is safe.

Monitoring and Precautions:
Before starting treatment, your doctor will perform blood tests and health checks to ensure the medication is appropriate for you. Regular monitoring will continue throughout the treatment to track your response and manage any potential side effects.

Uses of Brukinsa 80mg Capsule

Brukinsa 80mg Capsule is FDA-approved for the treatment of:

Mantle Cell Lymphoma (MCL) – in adults who’ve had at least one previous treatment

Chronic Lymphocytic Leukaemia (CLL) or Small Lymphocytic Lymphoma (SLL)

WaldenstrΓΆm’s Macroglobulinemia (WM)

Marginal Zone Lymphoma (MZL) – after treatment with an anti-CD20 medicine

Follicular Lymphoma (FL) – limited use or under review in some places

Therapeutic Effects of Brukinsa 80mg Capsule

Inhibits Cancer Cell Growth: Brukinsa blocks Bruton's tyrosine kinase (BTK), a protein that helps certain blood cancer cells survive and multiply. Slows or Stops Disease Progression: By interfering with BTK, it slows the spread of cancer in the body. Reduces Tumor Size: In some patients, it can shrink cancerous lymph nodes or masses. Improves Blood Counts: By controlling the cancer, it can help restore or stabilize red and white blood cell levels affected by the disease. Helps Manage Relapsed or Refractory Blood Cancers: Particularly effective for patients who have already undergone previous treatments but whose disease has returned or not fully responded. Symptom Relief: By controlling cancer growth, Brukinsa may reduce symptoms such as fatigue, fever, night sweats, and swelling associated with blood cancers.

Interaction of Brukinsa 80mg Capsule with other drugs

Some medicines can interact with Brukinsa 80mg Capsule, making it less effective or increasing the risk of side effects. Make sure to tell your doctor about all medicines, vitamins, or herbal supplements you’re taking. Here are some serious interactions to be aware of: Strong antifungals or antibiotics (like ketoconazole or clarithromycin) can raise the levels of Zanubrutinib in your body, which may cause side effects. Medicines that lower Zanubrutinib levels, like rifampin or phenytoin, might make it less effective. Blood thinners (like warfarin or clopidogrel) can increase your risk of bleeding. Heart rhythm drugs or medications that affect the heartbeat can lead to complications when taken together with Zanubrutinib. Live vaccines should be avoided during treatment and for a while after stopping the medicine. Always check with your doctor before starting any new medication.

More Information about Brukinsa 80mg Capsule

Word of Advice for Brukinsa 80mg Capsule (Zanubrutinib): Take as Prescribed: Always take Brukinsa exactly as directed by your doctor. Do not change the dose or stop treatment without medical guidance. Monitor Your Health: Your doctor will perform regular blood tests and checkups to monitor your response and detect any side effects early. Report Symptoms Promptly: Contact your doctor immediately if you experience unusual bleeding, bruising, infections, fever, heart problems, or severe fatigue. Avoid Certain Medications: Inform your doctor about all prescription drugs, over-the-counter medicines, vitamins, and supplements, as some may interact with Brukinsa. Liver and Heart Precautions: People with liver disease or heart conditions should be closely monitored while taking this medicine. Pregnancy and Breastfeeding: Brukinsa is not recommended during pregnancy or breastfeeding unless approved by your doctor. Use effective contraception during treatment if applicable. Storage: Keep the capsules in a cool, dry place, away from children and pets.

How to consume Brukinsa 80mg Capsule

You can take Brukinsa 80mg Capsule by mouth, usually once or twice a day, depending on your doctor’s advice. You can take it with or without food, but make sure to take it around the same time each day. Swallow the capsule whole; don’t crush or chew it

Side Effects of Brukinsa 80mg Capsule

Common Side Effects:
Diarrhea
Muscle pain
Cough
Rash
Low white blood cell count
Tiredness
Bruising easily
Serious Side Effects:
Serious infections (fever, chills, shortness of breath)
Bleeding or blood in stool/urine
Irregular heartbeat or chest pain
Liver problems (yellowing of skin or eyes)
Severe allergic reactions (swelling, rash, difficulty breathing)

Safety Advice for Brukinsa 80mg Capsule

Pregnancy
Unsafe
Brukinsa 80mg Capsule may cause harm to the unborn baby and is not recommended during pregnancy. Women of childbearing age should use effective birth control during treatment and for at least one week after stopping the medicine.
Breast Feeding-Unsafe
Breast Feeding
Unsafe
It is unknown whether Brukinsa 80mg Capsule passes into breast milk. However, due to the potential risk to the infant, breastfeeding should be avoided during and for at least one week after the last dose.
Lungs-Consult Your Doctor
Lungs
Consult Your Doctor
Brukinsa 80mg Capsule may increase the risk of infections, including lung infections. Inform your doctor immediately if you develop cough, fever, or shortness of breath.
Liver-Consult Your Doctor
Liver
Consult Your Doctor
Patients with liver disease should take Brukinsa 80mg Capsule only under strict medical supervision, as the medicine is processed by the liver. Dose adjustments may be required.
Alcohol-Unsafe
Alcohol
Unsafe
Avoid drinking alcohol while taking Brukinsa 80mg Capsule, as it can increase the risk of liver problems and reduce the body’s ability to fight infections.
Driving-Consult Your Doctor
Driving
Consult Your Doctor
Brukinsa 80mg Capsule may cause tiredness or dizziness in some people. Avoid driving or operating machinery until you know how the medicine affects you.

Word of Advice for Brukinsa 80mg Capsule

Word of Advice for Brukinsa 80mg Capsule (Zanubrutinib): Take as Prescribed: Always take Brukinsa exactly as directed by your doctor. Do not change the dose or stop treatment without medical guidance. Monitor Your Health: Your doctor will perform regular blood tests and checkups to monitor your response and detect any side effects early. Report Symptoms Promptly: Contact your doctor immediately if you experience unusual bleeding, bruising, infections, fever, heart problems, or severe fatigue. Avoid Certain Medications: Inform your doctor about all prescription drugs, over-the-counter medicines, vitamins, and supplements, as some may interact with Brukinsa. Liver and Heart Precautions: People with liver disease or heart conditions should be closely monitored while taking this medicine. Pregnancy and Breastfeeding: Brukinsa is not recommended during pregnancy or breastfeeding unless approved by your doctor. Use effective contraception during treatment if applicable. Storage: Keep the capsules in a cool, dry place, away from children and pets.

FAQs about Brukinsa 80mg Capsule

Q1. Q1. What is Brukinsa 80mg Capsule used for?

Brukinsa 80mg Capsule is used to treat certain blood cancers such as mantle cell lymphoma, chronic lymphocytic leukemia, and WaldenstrΓΆm’s macroglobulinemia. It helps slow down the growth of cancer cells by blocking a specific protein involved in their survival.

Q2. Q2. Is Zanubrutinib effective for stage 4 lymphoma?

Yes, Zanubrutinib has shown effectiveness in treating advanced stages of certain lymphomas, including stage 4 mantle cell lymphoma or CLL. It helps reduce cancer burden and improve quality of life, though individual responses may vary.

Q3. Q3. Can I take Brukinsa 80mg Capsule with food?

Yes, Brukinsa 80mg Capsule can be taken with or without food. However, take it at the same time every day and follow your doctor’s instructions carefully to maintain consistent blood levels.

Q4. Q4. How long should I take Brukinsa 80mg Capsule?

The duration of treatment depends on how well you respond to the medication and whether you experience any side effects. Some people may take it long-term, while others may need dose adjustments or switching based on progress.

Q5. Q5. What should I avoid while taking Brukinsa 80mg Capsule?

Avoid grapefruit juice, alcohol, and live vaccines during treatment. Also, avoid taking medicines that interact with Zanubrutinib without your doctor’s advice, especially blood thinners or antifungals.

Fact Box of Brukinsa 80mg Capsule

Molecule Name ZANUBRUTINIB
Marketer GLENMARK PHARMACEUTICALS LTD

References for Brukinsa 80mg Capsule

1.https://d1e94vsyskgtht.cloudfront.net/brukinsa/pdfs/brukinsa-patient-information.pdf
2.https://www.brukinsa.com/
3.https://www.drugs.com/zanubrutinib.html
4.https://www.cancerresearchuk.org/about-cancer/treatment/drugs/zanubrutinib
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Brukinsa 80mg Capsule
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120 Cap Capsule in Bottle

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