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Home β€Ί Medicine β€Ί Bortiva 3.5mg Injection
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Bortiva 3.5mg Injection

Prescription Required
Salt Composition BORTEZOMIB
Marketer GLS PHARMA LTD
Prepaid Only. Non-Returnable.
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Introduction to Bortiva 3.5mg Injection

Bortiva 3.5 mg Injection is a chemotherapy medication classified as a proteasome inhibitor and contains bortezomib as its active ingredient. It is used to treat multiple myeloma, a cancer of plasma cells in the bone marrow, and mantle cell lymphoma, a rare type of lymphoma affecting the lymph nodes. This injection is often administered alongside other chemotherapy drugs such as pegylated liposomal doxorubicin, rituximab, cyclophosphamide, doxorubicin, dexamethasone, prednisolone, or thalidomide, particularly in patients who have not received prior treatment and are not candidates for stem cell transplantation.

Common side effects may include pneumonia, loss of appetite, skin sensitivity, tingling or burning sensations, nausea, vomiting, diarrhea, mouth sores, constipation, muscle and bone pain, hair loss, fever, infections, itching, redness, dehydration, and digestive problems. Contact your doctor if any of these effects persist or become bothersome.

Do not use Bortiva 3.5 mg Injection if you are allergic to bortezomib or any of its ingredients, or if you have severe heart or lung conditions. Before starting treatment, inform your doctor if you have neuropathy (nerve damage), cardiac disorders, serious lung or pulmonary issues, posterior reversible encephalopathy syndrome (PRES), gastrointestinal problems, low platelet count (thrombocytopenia), low white blood cell count (neutropenia), tumor lysis syndrome, liver disorders, or diabetes, as this medication can affect blood sugar levels. Your healthcare provider will monitor you closely to prevent or manage potential complications.

Uses of Bortiva 3.5mg Injection

Treatment of multiple myeloma and mantle cell lymphoma.

Therapeutic Effects of Bortiva 3.5mg Injection

Bortiva 3.5mg Injection Injection works by exerting a toxic effect on cancer cells. It inhibits the 26S proteasome and blocks a major cell signaling pathway. This inhibition of the signaling pathway makes the cancer cells sensitive to chemotherapy. This medicine also enhances the build-up of a protein and minimizes cancer cell growth and multiplication.

Interaction of Bortiva 3.5mg Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Bortiva 3.5mg Injection and may cause undesirable side effects.

More Information about Bortiva 3.5mg Injection

Store unopened vials in the refrigerator (2 Β°C – 8 Β°C) and protect them from light. Keep this medicine out of sight and reach of children.

How to consume Bortiva 3.5mg Injection

Bortiva 3.5mg Injection is administered intravenously in your vein or subcutaneously under the skin. This injection should be given by a qualified healthcare professional experienced in the use of cytotoxic medications. Do not self-administer

Side Effects of Bortiva 3.5mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
Muscle cramps
Confusion, visual disturbances, seizures, and headache
Breathlessness
Swelling of feet
Changes in heartbeat
High blood pressure
Fainting and tiredness
Cough and chest tightness
Common
Pneumonia
Loss of appetite
Sensitivity, tingling and burning sensation of the skin
Nausea, vomiting, and diarrhea
Mouth ulcers
Constipation
Muscle and bone pain
Hair loss
Fever
Reduction in blood cell count
Reduced kidney function
Shivering
Infections
Itching and redness
Dehydration
Stomach problems
Difficulty sleeping, anxiety, mood swings, depressed mood

Safety Advice for Bortiva 3.5mg Injection

Breast Feeding
Unsafe
Bortiva 3.5mg Injection is unsafe to use during breastfeeding. Please discuss with your physician when it is safe to restart breastfeeding after this treatment.
Alcohol-Consult your doctor
Alcohol
Consult Your Doctor
It is unsafe to consume alcohol with this medication. Bortiva 3.5mg Injection may cause excessive drowsiness with alcohol. Please consult your doctor for more advice.
Liver-Consult your doctor
Liver
Consult Your Doctor
Inform your physician before starting this treatment if you have Hepatitis infection or liver disease. Your physician will monitor your liver functions regularly.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
It is unknown whether Bortiva 3.5mg Injection can be given to lung failure patients. Please consult your physician if you have any lung diseases.
Driving-unsafe
Driving
Unsafe
Avoid driving or using machinery if you experience side effects like fainting, dizziness, tiredness, or blurred vision.
Pregnancy-unsafe
Pregnancy
Unsafe
Bortiva 3.5mg Injection is unsafe to use during pregnancy unless clearly necessary. Both women of childbearing potential and men must use an effective contraception method during and three months after treatment.

Word of Advice for Bortiva 3.5mg Injection

It is advised that both men and women must use an effective contraception method during treatment and three months afterward. Treatment with Bortiva 3.5mg Injection can commonly cause a decrease in the number of red and white blood cells and platelets in your blood. Therefore, you will have to take regular blood tests before and during your treatment with bortezomib to check your blood cell counts regularly. Pregnant women should not handle this Injection as it contains cytotoxic agents. Using gloves and protective clothing is recommended to prevent skin contact.

FAQs about Bortiva 3.5mg Injection

Q1. Q1. What is Bortiva 3.5mg Injection used for?

Bortiva 3.5mg Injection is mainly indicated to treat mantle cell lymphoma and multiple myeloma.

Q2. Q2. Can I drive while taking Bortiva 3.5mg Injection?

Bortiva 3.5mg Injection may cause dizziness, tiredness, fainting, or blurred vision. Hence, avoid driving and operating heavy machines while this Injection

Q3. Q3. How is Bortiva 3.5mg Injection given?

Bortiva 3.5mg Injection is administered intravenously in your vein or subcutaneously under the skin by a doctor in a medical facility.

Q4. Q4. Is it safe to handle Bortiva 3.5mg Injection while pregnant?

No, Pregnant women should not handle Bortiva 3.5mg Injection as it contains cytotoxic agents. Using gloves and protective clothing is recommended to prevent skin contact.

Q5. Q5. What class of chemo is Bortiva 3.5mg Injection?

Bortiva 3.5mg Injection is a targeted therapy that belongs to the class of medicines called proteasome inhibitors.

Q6. Q6. Can I take Bortiva 3.5mg Injection when I am pregnant?

Avoid taking Bortiva 3.5mg Injection if you are pregnant, as it can cause harmful effects on the unborn baby. Females should use effective birth control methods during treatment and at least three months after treatment.

Q7. Q7. I am suffering from a Hepatitis infection. Can I take Bortiva 3.5mg Injection?

Bortiva 3.5mg Injection should not be used in patients with hepatitis infection because they might have a repeated attack of hepatitis, which can be fatal. If you have a history of hepatitis B infection, your doctor will carefully check you for signs of active hepatitis B.

Fact Box of Bortiva 3.5mg Injection

Molecule Name BORTEZOMIB
Marketer GLS PHARMA LTD

References for Bortiva 3.5mg Injection

1.STADA, Electronic Medicines Compendium (EMC), [Revised on Nov 2021] [Accessed on 30 Nov 2022],
2.Takeda Pharmaceuticals U.S.A., Inc., [Revised on Aug 2022] [Accessed on 30 Nov 2022],
3.Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
4.KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
5.H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056
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Bortiva 3.5mg Injection
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3.5 ML Injection in Vial

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