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Home β€Ί Medicine β€Ί Azapharm 100mg Injection

Azapharm 100mg Injection

Prescription Required
Salt Composition AZACITIDINE
Marketer PHARMACO INDUSTRIES PVT. LTD.
Prepaid Only. Non-Returnable.
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This medicine is prepaid
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Introduction to Azapharm 100mg Injection

Azapharm 100 mg Injection is used to treat adults with Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) who are not suitable candidates for stem cell transplantation.

In Myelodysplastic Syndrome, the bone marrow does not function properly, resulting in reduced production of healthy blood cells. Acute Myeloid Leukemia is a cancer of the bone marrow in which immature and abnormal blood cells are produced and released into the bloodstream, disrupting normal blood cell formation.

Uses of Azapharm 100mg Injection

Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Haemopoietic stem cell transplant

Intermediate-2 and High-risk Myelodysplastic syndrome (MDS)

Therapeutic Effects of Azapharm 100mg Injection

Restores normal blood cell production: It helps the bone marrow produce healthier red blood cells, white blood cells, and platelets. Slows disease progression: Azapharm reduces the growth and spread of abnormal cells in conditions like Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML). Improves bone marrow function: By correcting abnormal DNA changes in bone marrow cells, it helps improve overall marrow activity. Reduces transfusion dependence: Many patients experience a reduced need for blood transfusions over time. Controls cancer cell growth: It inhibits the multiplication of immature and defective blood cells, helping to manage leukemia.

Interaction of Azapharm 100mg Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Hemazide 100 mg injection and cause undesirable side effects.

More Information about Azapharm 100mg Injection

Azapharm 100 mg Injection contains azacitidine, a chemotherapy medicine used mainly to treat certain blood and bone marrow disorders. It is prescribed for adults with Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) who are not eligible for stem cell transplantation. How it works Azacitidine works by altering abnormal DNA activity in bone marrow cells. This helps slow or stop the growth of abnormal cells and allows healthier blood cells to develop. Administration Azapharm is supplied as a powder for injection and is reconstituted before use. It is given either subcutaneously (under the skin) or intravenously (into a vein) by a healthcare professional. Monitoring during treatment Frequent blood tests are required to monitor blood counts, as the medicine can lower red blood cells, white blood cells, and platelets, especially during early treatment cycles. Possible side effects Common side effects include nausea, vomiting, constipation or diarrhea, fatigue, fever, injection-site reactions, and reduced appetite. Serious side effects such as infections or bleeding may occur due to low blood cell counts and require immediate medical attention. Precautions Inform your doctor if you have liver, kidney, or heart problems. Avoid pregnancy during treatment and follow effective contraception as advised. Breastfeeding is not recommended during therapy. Report any signs of infection, unusual bleeding, or severe weakness promptly. Storage Unopened vials should be stored as directed on the label. Once reconstituted, the solution should be used within the recommended time frame under medical guidance.

How to consume Azapharm 100mg Injection

Take Azapharm 100mg Injection only under the supervision of your physician. Your physician will decide the dose based on your height, weight, and general condition. It shall be given under the skin of your thigh, stomach, or upper arm.

Side Effects of Azapharm 100mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
Unexpected bleeding, with blood in stool and urine
Fever
Pneumonia is characterised by chest pain or breathlessness.
Allergic reaction with symptoms of swelling of lips, itching, or rashes.
Seizures, loss of consciousness, severe headache, or bleeding in the brain
Frequent urination with pain or burning sensation
Common:
Disturbances in the blood count (RBC, WBC, Platelets)
Nausea, vomiting, diarrhea
Constipation
Tiredness
Skin reactions like redness and pain at the site of injection
Decreased appetite
Dizziness
Pain in extremities
Joint pain
Stomach pain
Headache
Sore nose and throat
Rashes and bruising

Safety Advice for Azapharm 100mg Injection

Pregnancy
Unsafe
Azapharm 100mg Injection could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.
Breast Feeding-Unsafe
Breast Feeding
Unsafe
Breastfeeding is not intended for patients on Azapharm 100mg Injection therapy. Consult your physician for advice.
Lungs-Consult Your Doctor
Lungs
Consult Your Doctor
It is not known whether it is safe to administer Azapharm 100mg Injection in lung failure patients. Please consult your doctor.
-
Liver-Consult Your Doctor
Liver
Consult Your Doctor
Inform your physician if you have been told that you have a tumor in the liver cells.
Alcohol-Consult Your Doctor
Alcohol
Consult Your Doctor
It is not known whether it is safe to consume alcohol with Azapharm 100mg Injection. Please consult your doctor.
Driving-Unsafe
Driving
Unsafe
It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking Hemazide 100 mg injection.

Word of Advice for Azapharm 100mg Injection

Azapharm 100 mg Injection should be administered only under the supervision of an experienced healthcare professional. Regular blood tests are essential during treatment to monitor blood cell counts and liver and kidney function. Inform your doctor if you have a history of infections, liver disease, kidney problems, or bleeding disorders before starting therapy. This medicine can weaken the immune system, so avoid close contact with people who have infections and report fever, chills, or signs of infection immediately. Use effective contraception during treatment and for a period recommended by your doctor, as this medicine may harm an unborn baby. Breastfeeding should be avoided during treatment unless your doctor advises otherwise. Do not miss scheduled doses, and never change the dose or stop treatment without consulting your doctor. Contact your healthcare provider promptly if you notice unusual bruising, bleeding, severe fatigue, or shortness of breath.

FAQs about Azapharm 100mg Injection

Q1. Q1. How to use Azapharm 100mg Injection?

Take Azapharm 100mg Injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. Azapharm 100mg Injection is administered under the skin of your thigh, stomach, or upper arm.

Q2. Q2. Does Azapharm 100mg Injection cause hair loss?

No, Azapharm 100mg Injection does not cause hair loss even after using it for a prolonged period of time.

Q3. Q3. How does Azapharm 100mg Injection work?

Azapharm 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

Q4. Q4. Is Azapharm 100mg Injection chemotherapy?

Yes. Azapharm 100mg Injection is chemotherapy used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).

Q5. Q5. What are the side effects of Azapharm 100mg Injection?

The common side effects of Azapharm 100mg Injection are nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat, and nose.

Fact Box of Azapharm 100mg Injection

Molecule Name AZACITIDINE
Marketer PHARMACO INDUSTRIES PVT. LTD.

References for Azapharm 100mg Injection

1.K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, [May 2003], 60(4):721-741, [Accessed on 5th Apr 2021]
2.Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018 [Accessed on 3rd Apr 2021]
3.Dr.Reddy’s Laboratories, [Revised on 8th Nov 2018] [Accessed on 5th Apr 2021]
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Azapharm 100mg Injection
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