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Home β€Ί Medicine β€Ί Azadine O 200mg Tablet
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Azadine O 200mg Tablet

Prescription Required
Salt Composition AZACITIDINE
Marketer INTAS PHARMACEUTICALS LTD
Prepaid Only. Non-Returnable.
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This medicine is prepaid
only and cannot be
returned once delivered.
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Introduction to Azadine O 200mg Tablet

Azadine O 200mg Tablet is used to treat adults with Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) who are not eligible for a stem cell transplant.

In Myelodysplastic Syndrome, the bone marrow is unable to produce enough healthy blood cells, leading to a shortage of functional blood components.

Acute Myeloid Leukemia is a type of cancer in the bone marrow in which immature, improperly developed blood cells are released into the bloodstream, disrupting normal blood cell production.

Uses of Azadine O 200mg Tablet

Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Haemopoietic stem cell transplant
Intermediate-2 and High-risk Myelodysplastic syndrome (MDS)

Therapeutic Effects of Azadine O 200mg Tablet

In MDS and AML, the development of tumor cells is caused by the process of transcriptional repression of various genes, which is due to the hypermethylation of DNA. Transcriptional repression is a process where proteins bind directly or indirectly to DNA and control the activity of copying a specific gene or a set of genes. The active form of Azadine O 200mg Tablet binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

Interaction of Azadine O 200mg Tablet with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Hemazide 100 mg injection and cause undesirable side effects.

More Information about Azadine O 200mg Tablet

Store at room temperature (15-30Β°C). If the product is reconstituted, it must be used immediately; if not, store at 2-8Β°C for not more than 8 hours. Keep the injection out of sight and reach of children.

How to consume Azadine O 200mg Tablet

Take Azadine O 200mg Tablet only under the supervision of your physician. Your physician will decide the dose based on your height, weight, and general condition. It shall be given under the skin of your thigh, stomach, or upper arm.

Side Effects of Azadine O 200mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
Unexpected bleeding, with blood in stool and urine
Fever
Pneumonia is characterised by chest pain or breathlessness.
Allergic reaction with symptoms of swelling of lips, itching, or rashes.
Seizures, loss of consciousness, severe headache, or bleeding in the brain
Frequent urination with pain or burning sensation
Common:
Disturbances in the blood count (RBC, WBC, Platelets)
Nausea, vomiting, diarrhea
Constipation
Tiredness
Skin reactions like redness and pain at the site of injection
Decreased appetite
Dizziness
Pain in extremities
Joint pain
Stomach pain
Headache
Sore nose and throat
Rashes and bruising

Safety Advice for Azadine O 200mg Tablet

Breast Feeding
Unsafe
Breastfeeding is not intended for patients on Azadine O 200mg Tablet therapy. Consult your physician for advice.
Alcohol-Consult your doctor
Alcohol
Consult Your Doctor
It is not known whether it is safe to consume alcohol with Azadine O 200mg Tablet. Please consult your doctor.
Liver-Consult your doctor
Liver
Consult Your Doctor
Inform your physician if you have been told that you have a tumor in the liver cells.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
It is not known whether it is safe to administer Azadine O 200mg Tablet in lung failure patients. Please consult your doctor.
Driving-unsafe
Driving
Unsafe
It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking Azadine O 200mg Table.
Pregnancy-unsafe
Pregnancy
Unsafe
Azadine O 200mg Tablet could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.

Word of Advice for Azadine O 200mg Tablet

Inform the doctor if the patient has any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects in the developing baby. Take this injection only under the supervision of a physician. Doctors will decide the dose based on the patient's height, weight, and general condition. It is administered under the skin of your thigh, stomach or upper arm.

FAQs about Azadine O 200mg Tablet

Q1. Q1. How to use Azadine O 200mg Tablet?

Take Azadine O 200mg Tablet only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. Azadine O 200mg Tablet is administered under the skin of your thigh, stomach, or upper arm.

Q2. Q2. Is it safe to drive after taking Azadine O 200mg Tablet?

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking this medication.

Q3. Q3. What are the side effects of Azadine O 200mg Tablet?

The common side effects of Azadine O 200mg Tablet are nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat, and nose.

Q4. Q4. Is Azadine O 200mg Tablet chemotherapy?

Yes. Azadine O 200mg Tablet is chemotherapy used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).

Q5. Q5. How does Azadine O 200mg Tablet work?

Azadine O 200mg Tablet binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

Q6. Q6. Does Azadine O 200mg Tablet cause hair loss?Does Azadine O 200mg Tablet cause hair loss?

No, Azadine O 200mg Tablet does not cause hair loss even after using it for a prolonged period of time.

Fact Box of Azadine O 200mg Tablet

Molecule Name AZACITIDINE
Marketer INTAS PHARMACEUTICALS LTD

References for Azadine O 200mg Tablet

1.K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, [May 2003], 60(4):721-741, [Accessed on 5th Apr 2021]
2.Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018 [Accessed on 3rd Apr 2021]
3.Dr.Reddy’s Laboratories, [Revised on 8th Nov 2018] [Accessed on 5th Apr 2021]
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Azadine O 200mg Tablet
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