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Home β€Ί Medicine β€Ί Alunbrig 180mg Tablet
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Alunbrig 90mg Tablet
TAKEDA PHARMACEUTICALS...
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Alunbrig 180mg Tablet

Prescription Required
Salt Composition BRIGATINIB
Marketer TAKEDA PHARMACEUTICALS INDIA PVT LTD
Prepaid Only. Non-Returnable.
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Introduction to Alunbrig 180mg Tablet

Alunbrig 180 mg Tablet is an anticancer medication containing Brigatinib as its active ingredient. It belongs to a class of medicines known as tyrosine kinase inhibitors (TKIs), which work by blocking abnormal proteins that promote the growth and survival of cancer cells.

This medicine is prescribed for patients with ALK-positive (anaplastic lymphoma kinase–positive) non-small cell lung cancer (NSCLC) who have experienced disease progression or are unable to tolerate previous ALK inhibitor therapy. Alunbrig helps slow or stop the multiplication and spread of cancer cells by targeting specific enzymes involved in tumor development.

Alunbrig 180 mg Tablet should not be used by individuals with a known allergy to Brigatinib or any of the ingredients in the formulation. Discontinue the medicine and seek immediate medical attention if you experience signs of an allergic reaction, such as skin rash, swelling, or difficulty breathing.

If you are pregnant, planning to become pregnant, or think you may be pregnant, consult your doctor before starting this medication, as it may cause serious harm to the unborn baby. Likewise, inform your healthcare provider if you are breastfeeding or planning to breastfeed. Your doctor will review your medical history and current medications to ensure the safe and appropriate use of Alunbrig.

Uses of Alunbrig 180mg Tablet

Alunbrig 180mg Tablet is used for:

Treatment of ALK-positive non-small cell lung cancer (NSCLC)

Managing disease progression in patients previously treated with other ALK inhibitors

Reducing tumor growth and preventing metastasis

Therapeutic Effects of Alunbrig 180mg Tablet

Effectively treats ALK-positive non-small cell lung cancer (NSCLC) Inhibits abnormal anaplastic lymphoma kinase (ALK) activity that drives cancer cell growth Helps slow or stop the progression of cancer by preventing cancer cells from multiplying and spreading Reduces tumor size and controls disease in patients who have progressed on or are intolerant to previous ALK inhibitors Demonstrates activity against cancer that has spread to the brain (brain metastases) Improves disease control and progression-free survival Generally better tolerated than conventional chemotherapy, supporting a better quality of life during treatment

Interaction of Alunbrig 180mg Tablet with other drugs

Alunbrig 180mg Tablet may interact with: Strong CYP3A inhibitors (e.g., ketoconazole) that can increase brigatinib levels in the blood CYP3A inducers (e.g., rifampin) that can reduce its effectiveness Other anticancer drugs, increasing the risk of side effects like heart rhythm problems or lung toxicity Always inform your doctor of all other medications, including over-the-counter drugs and herbal supplements.

More Information about Alunbrig 180mg Tablet

Alunbrig 180 mg Tablet contains Brigatinib, a targeted anticancer therapy used for the treatment of ALK-positive non-small cell lung cancer (NSCLC). It works by selectively inhibiting abnormal ALK activity, which helps slow the growth and spread of cancer cells. This medicine is usually prescribed after confirmation of ALK gene rearrangement and may be used in patients who have previously received other ALK inhibitors. Alunbrig is taken orally and may be taken with or without food. To reduce the risk of side effects, treatment is often started at a lower dose and gradually increased as advised by the physician. Regular medical monitoring is required during treatment, including checks of blood pressure, liver function, blood sugar levels, heart rate, and lung function. Inform your doctor immediately if you experience symptoms such as shortness of breath, persistent cough, vision problems, muscle pain, or unusual fatigue. Avoid consuming grapefruit or grapefruit juice while taking Alunbrig, as it may affect how the medicine works. Store the tablet at room temperature, away from moisture and direct sunlight, and keep it out of reach of children. Always take Alunbrig exactly as directed by your doctor and do not share this medication with others. If you miss a dose, follow your physician’s instructions rather than taking an extra tablet.

How to consume Alunbrig 180mg Tablet

Take exactly as prescribed by your oncologist Usually taken once daily, with or without food Swallow the tablet whole; do not crush, chew, or split Follow the prescribed dosage schedule strictly If a dose is missed, take it as soon as you remember unless it’s near the next dose. Do not double the dose.

Side Effects of Alunbrig 180mg Tablet

Common side effects:
Nausea
Fatigue
Diarrhea
Increased blood pressure
Cough
Serious side effects (seek medical help immediately):
Lung problems (pneumonitis, interstitial lung disease)
Liver enzyme abnormalities
Severe allergic reactions (rash, swelling, difficulty breathing)
High blood pressure
Visual disturbances

Safety Advice for Alunbrig 180mg Tablet

Pregnancy
Unsafe
It is recommended to avoid this medication during pregnancy as Alunbrig 180mg Tablet may cause fetal harm. Inform your doctor if you are pregnant, suspect pregnancy, or planning to become pregnant before starting treatment.
Breast Feeding-Consult Your Doctor
Breast Feeding
Consult Your Doctor
It is unknown whether Alunbrig 180mg Tablet passes into breast milk. Consult your doctor before using this medicine while breastfeeding.
Lungs-Consult Your Doctor
Lungs
Consult Your Doctor
Alunbrig 180mg Tablet may cause serious lung-related side effects such as interstitial lung disease or pneumonitis. Inform your doctor if you have a history of lung problems or experience shortness of breath before starting treatment
Liver-Consult Your Doctor
Liver
Consult Your Doctor
Alunbrig 180mg Tablet is metabolized by the liver and may cause elevated liver enzymes or liver dysfunction. Inform your doctor if you have liver disease before starting treatment.
Alcohol-Consult Your Doctor
Alcohol
Consult Your Doctor
There is limited data on the safety of alcohol use with Alunbrig 180mg Tablet . It may increase the risk of side effects such as drowsiness or liver issues. Please consult your physician.
Driving-Consult Your Doctor
Driving
Consult Your Doctor
Alunbrig 180mg Tablet may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you understand how the drug affects you.

Word of Advice for Alunbrig 180mg Tablet

Take Alunbrig 180 mg Tablet exactly as prescribed by your doctor and do not change the dose or stop the medication without medical advice. Regular monitoring through blood tests and medical check-ups may be required during treatment. Inform your doctor about all existing medical conditions, especially lung problems, heart disease, high blood pressure, liver disorders, or vision problems. Avoid pregnancy while taking this medicine and use effective contraception during treatment and for the period advised by your doctor after stopping the drug, as Alunbrig may harm the unborn baby. Breastfeeding is not recommended during treatment unless advised otherwise by your physician. Do not consume grapefruit or grapefruit juice while using Alunbrig, as it may interfere with the medicine’s effectiveness. Seek immediate medical attention if you experience symptoms such as breathing difficulty, chest pain, severe fatigue, vision changes, or signs of an allergic reaction. Always follow your healthcare provider’s guidance to ensure safe and effective treatment.

FAQs about Alunbrig 180mg Tablet

Q1. Q1. What is Alunbrig 180mg Tablet used for?

Alunbrig 180mg Tablet is primarily used for the treatment of ALK-positive non-small cell lung cancer (NSCLC) and managing disease progression in patients previously treated with other ALK inhibitors.

Q2. Q2. Can Alunbrig 180mg Tablet be used during pregnancy?

No, Alunbrig 180mg Tablet is not recommended during pregnancy as it may cause serious harm to the developing fetus. Always consult your doctor before starting treatment if you are pregnant or planning pregnancy.

Q3. Q3. How should I take Alunbrig 180mg Tablet?

Take Alunbrig 180mg Tablet exactly as prescribed by your doctor, usually once daily, with or without food. Do not crush, chew, or split the tablets. Follow your doctor’s dosage schedule carefully.

Q4. Q4. What should I do if I miss a dose of Alunbrig 180mg Tablet?

If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose to make up for the missed one.

Q5. Q5. Are there any serious side effects I should watch for?

Yes, report any difficulty breathing, severe rash, swelling, liver issues, or heart problems to your doctor immediately, as these could be serious side effects requiring urgent medical attention.

Q6. Q6. Is it safe to drive while taking Alunbrig 180mg Tablet?

Alunbrig 180mg Tablet may cause dizziness or fatigue in some patients. It is advised to avoid driving or operating heavy machinery until you know how the medication affects you.

Fact Box of Alunbrig 180mg Tablet

Molecule Name BRIGATINIB
Marketer TAKEDA PHARMACEUTICALS INDIA PVT LTD

References for Alunbrig 180mg Tablet

Scientific studies and manufacturer pharmaceutical data sheets.
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Alunbrig 180mg Tablet
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