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Home β€Ί Medicine β€Ί Alecensa 150mg Capsule
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Alecensa 150mg Capsule

Prescription Required
Salt Composition ALECTINIB HYDROCHLORIDE
Marketer ROCHE PRODUCTS
Prepaid Only. Non-Returnable.
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This medicine is prepaid
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Introduction to Alecensa 150mg Capsule

Alecensa 150 mg Capsule contains the active ingredient Alectinib Hydrochloride. It is an anticancer medication used in the treatment of non-small cell lung cancer (NSCLC), a type of lung cancer that can be advanced and spread to other parts of the body. Alecensa is effective in treating NSCLC that has metastasized, including spread to the brain. Compared to traditional chemotherapy, it is generally well tolerated and is associated with fewer side effects, helping patients maintain a better quality of life and continue their daily activities during treatment.

Before starting Alecensa, inform your doctor if you are using oral contraceptives, as this medicine may reduce their effectiveness. Notify your healthcare provider if you have any history of stomach, intestinal, abdominal, heart conditions, lung inflammation, or lactose intolerance.

Use adequate sun protection during treatment and continue for at least 7 days after stopping Alecensa, as the medication may increase sensitivity to sunlight. Consumption of grapefruit and Seville oranges should be avoided or done with caution, as they may interfere with the effectiveness of this medicine.

Uses of Alecensa 150mg Capsule

Alecensa 150mg Capsule has been approved to treat ALK-positive lung cancer (NSCLC) that has spread to other organs.

Therapeutic Effects of Alecensa 150mg Capsule

The therapeutic effects of Alecensa 150mg Capsule are related to its ability to target a specific genetic mutation called anaplastic lymphoma kinase (ALK) in non-small cell lung cancer (NSCLC) cells. By inhibiting the ALK protein, this medication can slow down or stop the growth and spread of cancer cells that have the ALK genetic mutation.

Interaction of Alecensa 150mg Capsule with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Alecensa 150mg Capsule and reduce effectiveness by causing undesirable side effects.

More Information about Alecensa 150mg Capsule

Alecensa 150mg Capsule should be stored at room temperature between 68Β°F to 77Β°F (20Β°C to 25Β°C). Keep in the original container. Keep away from light, moisture, and heat. Once opened, the blister pack should be used within 14 days.

How to consume Alecensa 150mg Capsule

Alecensa 150mg Capsule is taken orally as a capsule and should be taken with food. The capsules should be swallowed whole with water and should not be crushed, chewed, or opened. The dosage and duration of treatment will depend on the individual's condition and response to the medication and should be determined by a healthcare provider. If a dose is missed, it should be taken as soon as possible unless it is within 12 hours of the next dose, in which case the missed dose should be skipped. Double doses should not be taken to make up for a missed dose.

Side Effects of Alecensa 150mg Capsule

Like all medications, Alecensa 150mg Capsule can cause side effects, although not everyone who takes it will experience them.
Serious:
Yellowing of skin and white parts of the eye
Dark urine
Pain at the right side of the stomach
Skin itching
Loss of appetite
Nausea and vomiting
Easy bleeding or bruising
Persistent muscle pain
Tender or weak muscles
Loss of consciousness
Dizziness
Low blood pressure
Difficulty breathing
Cough with or without mucous
Fever
Common:
Elevated liver enzymes
Rashes
Odema (fluid build-up causing swelling)
Fatigue
Diarrhea
Constipation
Weight gain
Inflammation in mouth
Light sensitivity
Changes in taste

Safety Advice for Alecensa 150mg Capsule

Breast Feeding
Consult Your Doctor
It is unknown whether Alecensa 150mg Capsule is excreted in milk. So it is better to consult a healthcare provider if you are a breastfeeding mother before taking this medication.
Alcohol-unsafe
Alcohol
Unsafe
Alcohol consumption can have negative effects on the immune system and may interfere with the effectiveness of cancer therapies. So it is recommended to avoid taking alcohol while taking.
Liver-unsafe
Liver
Unsafe
Alecensa 150mg Capsule can cause liver damage or liver failure in some people, so it is important to monitor liver function during treatment with this medication. Before starting treatment, a healthcare provider will perform blood tests to assess liver function.
Lungs-safe
Lungs
Safe
Alecensa 150mg Capsule is safe to use in lung patients. It can be effective in treating NSCLC, it is not without potential side effects. But it is important to monitor lung function regularly during treatment with this medication.
Driving-unsafe
Driving
Unsafe
Patients receiving Alecensa 150mg Capsule are advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairment in their ability to drive or operate machinery safely.
Pregnancy-unsafe
Pregnancy
Unsafe
Alecensa 150mg Capsule is not safe for use during pregnancy because it can harm to developing baby.

Word of Advice for Alecensa 150mg Capsule

Alecensa 150mg Capsule is a powerful medication that can have potentially serious side effects. Therefore, following your healthcare provider's instructions for taking the medication and reporting any side effects or changes in your health is important. Women taking contraceptive measures should inform a doctor prior the treatment. If you are a woman who could become pregnant, use effective birth control during the treatment and for at least three months after the last dose. Tell your doctor prior taking medication, if you have any stomach, intestine, abdomen, heart, or lung inflammation. It is recommended that patients undergoing cancer treatment eat a diet rich in fruits, vegetables, whole grains, and lean proteins and limit their intake of processed and high-fat foods. Drinking plenty of water and staying hydrated is also important.

FAQs about Alecensa 150mg Capsule

Q1. Q1. What is ALK Positive lung cancer?

ALK positive lung cancer is a subset of lung cancer which is common in non smokers aged less than 55 years. ALK is a protein that stands for anaplastic lymphoma Kinase and mutation in this gene causes lung cancer cells to grow in a rapid fashion.

Q2. Q2. Can Alecensa 150mg Capsule cause weight gain?

Weight gain is a potential side effect of Alecensa 150mg Capsule, although it is not very common. If you notice unexplained weight gain while taking it, notify your healthcare provider.

Q3. Q3. Can Alecensa 150mg Capsule cause mood changes or depression?

Mood changes and depression have been reported in some patients taking Alecensa 150mg Capsule. If you experience any changes in your mood or feelings of depression while taking this Capsule, notify your healthcare provider. They may recommend additional support or treatment for depression.

Q4. Q4. Is Alecensa 150mg Capsule used in patients with brain metastases?

Alecensa 150mg Capsule has been shown to be effective in treating brain metastases in patients with ALK-positive NSCLC. It can cross the blood-brain barrier and reach the brain tissue, which may help to control the growth of cancer cells in the brain.

Q5. Q5. Can I use Alecensa 150mg Capsule if I have kidney problems?

Alecensa 150mg Capsule does not appear to be significantly metabolized by the kidneys, so it may be used in patients with mild to moderate kidney problems without dosage adjustment. However, patients with severe kidney problems may need dosage adjustments or additional monitoring.

Fact Box of Alecensa 150mg Capsule

Molecule Name ALECTINIB HYDROCHLORIDE
Marketer ROCHE PRODUCTS

References for Alecensa 150mg Capsule

1.Roche, Electronic Medicines Compendium (EMC), [Revised on January 2022] [Accessed on 15th April 2023]
2.Genentech, Inc., [Revised on September 2021] [Accessed on 15th April 2023],
3.Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.
4.Genentech , Inc.U.S FDA (Food and Drug Safety Administration), [ Last Revised November 2016], [Accessed on 15th April 2023],
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Alecensa 150mg Capsule
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