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Home β€Ί Medicine β€Ί Acabrunat 100mg Capsule
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Acabrunat 100mg Capsule

Prescription Required
Salt Composition ACALABRUTINIB
Marketer NATCO PHARMA LTD
Prepaid Only. Non-Returnable.
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This medicine is prepaid
only and cannot be
returned once delivered.
39% OFF
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Introduction to Acabrunat 100mg Capsule

Acabrunat 100mg Capsule is an anticancer medication that contains acalabrutinib as its active ingredient. It belongs to a group of medicines known as Bruton’s tyrosine kinase (BTK) inhibitors. This medicine is used in the treatment of mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), and small lymphocytic lymphoma (SLL). These conditions are cancers of lymphocytes, a type of white blood cell that plays a key role in the immune system. The disorders differ based on the location of the cancer and the specific lymphocytes involved.

Before starting treatment with Acabrunat 100mg Capsule, patients should inform their doctor if they have recently undergone surgery, have a history of bleeding disorders, heart rhythm abnormalities, or ongoing infections, or if they are pregnant or breastfeeding. This medicine is not recommended for use in children or adolescents under 18 years of age.

Acabrunat 100mg Capsule may increase the risk of bleeding. Patients should be closely monitored for any signs of bleeding and should avoid using other medicines that may further increase this risk, such as blood-thinning medications, unless advised by a healthcare professional.

Uses of Acabrunat 100mg Capsule

The Acabrunat 100mg Capsule is used in the treatment of

Chronic lymphocytic leukemia
Small lymphocytic lymphoma
Mantle cell lymphoma

Therapeutic Effects of Acabrunat 100mg Capsule

The therapeutic effect of Acabrunat 100mg Capsule is to inhibit the activity of Bruton's tyrosine kinase (BTK), a protein that is essential for the survival and growth of cancer cells in certain types of lymphomas and leukemias. By blocking BTK, it can help to slow down or even stop the growth and spread of cancer cells, which can lead to a reduction in tumor size, an improvement in symptoms, and a delay in disease progression.

Interaction of Acabrunat 100mg Capsule with other drugs

Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Acabrunat 100mg Capsule and reduce effectiveness by causing undesirable side effects.

More Information about Acabrunat 100mg Capsule

Store in a refrigerator between 20Β°C to 25Β°C (68Β°F to 77Β°F). Keep away from moisture, heat, and light. It should not be frozen. Keep it in its original packaging until it is ready to be used. Keep out of the reach of children and pets.

How to consume Acabrunat 100mg Capsule

Acabrunat 100mg Capsule is typically taken orally, with or without food. The tablets should be swallowed whole, not crushed, chewed, or broken. The recommended dosage can vary depending on the type of cancer being treated and other factors such as your overall health and response to treatment. Do not take a double dose to make up for a missed dose.

Side Effects of Acabrunat 100mg Capsule

Like all medications, Acabrunat 100mg Capsules cause some side effects, although not everyone will experience them.
Serious:
Bleeding problems (bruising or bleeding)
Infections (pneumonia and sepsis)
High blood pressure
Heart problems (irregular heartbeat and chest pain)
Kidney failure
Common:
Headache
Diarrhea
Nausea
Fatigue
Muscle and joint pain
Bruising or bleeding easily
Upper respiratory tract infection
Rash or itching

Safety Advice for Acabrunat 100mg Capsule

Breast Feeding
Consult Your Doctor
It is unknown whether Acabrunat 100mg Capsule is excreted into human breast milk, so breastfeeding women should consult a doctor before taking it.
Alcohol-unsafe
Alcohol
Unsafe
Patients taking Acabrunat 100mg Capsules avoid or limit their alcohol consumption, as alcohol can exacerbate certain side effects of the medication, such as fatigue and depression.
Liver-unsafe
Liver
Unsafe
Acabrunat 100mg Capsule can affect the liver, elevating liver enzymes (AST, ALT) in some patients taking it. In rare cases, severe liver injury or failure has been reported.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
If you have a lung disease or lung cancer and are considering treatment with Acabrunat 100mg Capsule, it is important to discuss this medication's potential benefits and risks with your healthcare provider.
Driving-unsafe
Driving
Unsafe
Patients should always monitor their response to the Acabrunat 100mg Capsule medication and be cautious when driving or operating machinery if they experience any side effects that may impair their ability to do so safely.
Pregnancy-unsafe
Pregnancy
Unsafe
Acabrunat 100mg Capsule is unsafe during pregnancy. It can harm the developing fetus, so pregnancy should be avoided while taking this medicine.

Word of Advice for Acabrunat 100mg Capsule

If you have been prescribed Acabrunat 100mg Capsule, it is important to carefully read and understand the warnings and precautions associated with the medication. Patients require monitoring for signs of an allergic reaction. It can cause high blood pressure. Patients should check their blood pressure regularly. Report to your doctor if you develop a lesion or change in the appearance of an area on the skin. It increases the risk of infection, so patients should avoid close contact with infected persons. Patients with diabetes require close monitoring during treatment. Pregnancy and breastfeeding should be avoided during treatment. Always maintain a healthy and balanced diet to support your overall health and well-being.

FAQs about Acabrunat 100mg Capsule

Q1. Q1. Can I take Acabrunat 100mg Capsule if I have a history of bleeding disorders?

Patients with a history of bleeding disorders may be at an increased risk of bleeding while taking Acabrunat 100mg Capsule. Before starting treatment, your healthcare provider will evaluate your bleeding risk and may recommend additional monitoring or precautions.

Q2. Q2. Can I take Acabrunat 100mg Capsule if I have a history of heart disease?

Acabrunat 100mg Capsule can cause cardiac effects, including irregular heartbeat and atrial fibrillation. Patients with a history of heart disease should be closely monitored while taking it. Your healthcare provider may recommend additional monitoring or precautions.

Q3. Q3. How will this medication affect my blood?

Acabrunat 100mg Capsule can affect your blood in several ways. It may cause a decrease in the number of red blood cells, white blood cells, and platelets. This can lead to anemia, infections, and an increased risk of bleeding. Your healthcare provider will monitor your blood counts before and during treatment.

Q4. Q4. Can I take this medication if I have diabetes?

Acabrunat 100mg Capsule can be taken by patients with diabetes, but it is important to monitor blood sugar levels closely while taking this medication. It can cause an increase in blood sugar levels in some patients, which may require adjustments in diabetes medications or insulin dosages.

Q5. Q5. Can I go for Tooth extraction while taking this medication?

Patients taking Acabrunat 100mg Capsule should inform their dentist and healthcare provider if they need to have a tooth extraction or any other dental procedures. This is because it can increase the risk of bleeding and impair wound healing. Your dentist and healthcare provider may recommend temporarily stopping treatment before the dental procedure to reduce the risk of bleeding.

Fact Box of Acabrunat 100mg Capsule

Molecule Name ACALABRUTINIB
Marketer NATCO PHARMA LTD

References for Acabrunat 100mg Capsule

1.AstraZeneca, US Food and Drug Administration, [ Revised on Oct 2017], [ Accessed on 5th May 2023],
2.John C Byrd et al; Acalabrutinib monotherapy in patients with relapsed/refractory chronic lymphocytic leukemia: updated phase 2 results; Blood; Published on April 2020; [Accessed on5th May 2023];
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Acabrunat 100mg Capsule
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(You Save β‚Ή5,701.25)
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